Detalhe da pesquisa
1.
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer.
Cell
; 184(25): 6119-6137.e26, 2021 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34890551
2.
WRN helicase is a synthetic lethal target in microsatellite unstable cancers.
Nature
; 568(7753): 551-556, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30971823
3.
Transforming Growth Factor-ß Blockade in Pancreatic Cancer Enhances Sensitivity to Combination Chemotherapy.
Gastroenterology
; 165(4): 874-890.e10, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37263309
4.
Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer.
Oncologist
; 28(5): 425-432, 2023 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36807743
5.
Large-scale reforestation can increase water yield and reduce drought risk for water-insecure regions in the Asia-Pacific.
Glob Chang Biol
; 28(21): 6385-6403, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36054815
6.
Discovery of a selective inhibitor of doublecortin like kinase 1.
Nat Chem Biol
; 16(6): 635-643, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32251410
7.
How we treat advanced biliary tract cancers in the second-line setting.
Clin Adv Hematol Oncol
; 21(1): 35-42, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36638354
8.
Scalable nonparametric clustering with unified marker gene selection for single-cell RNA-seq data.
bioRxiv
; 2024 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38405697
9.
Mutation and cell state compatibility is required and targetable in Ph + acute lymphoblastic leukemia minimal residual disease.
bioRxiv
; 2024 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38915726
10.
Compressed phenotypic screens for complex multicellular models and high-content assays.
bioRxiv
; 2023 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36747859
11.
USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities.
Cell Rep Med
; 4(4): 101007, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37030295
12.
A Phase I Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-dose Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma.
Clin Cancer Res
; 29(24): 5047-5056, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37819936
13.
Oncogenic Drivers and Therapeutic Vulnerabilities in KRAS Wild-Type Pancreatic Cancer.
Clin Cancer Res
; 29(22): 4627-4643, 2023 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37463056
14.
Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.
Cancer Res
; 83(3): 441-455, 2023 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36459568
15.
Decoupling diffusional from dimensional control of signaling in 3D culture reveals a role for myosin in tubulogenesis.
J Cell Sci
; 123(Pt 17): 2877-83, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20682635
16.
Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner.
Exp Cell Res
; 317(13): 1860-71, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21640103
17.
RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.
Nat Commun
; 13(1): 3181, 2022 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35676246
18.
Secondary IDH1 resistance mutations and oncogenic IDH2 mutations cause acquired resistance to ivosidenib in cholangiocarcinoma.
NPJ Precis Oncol
; 6(1): 61, 2022 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36056177
19.
An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling.
J Cell Biol
; 174(2): 277-88, 2006 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16847103
20.
Opportunities for Utilization of DNA Repair Inhibitors in Homologous Recombination Repair-Deficient and Proficient Pancreatic Adenocarcinoma.
Clin Cancer Res
; 27(24): 6622-6637, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34285063