Pesquisa | BVS Educação Profissional em Saúde

1.

A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets.

Vlasschaert, Caitlyn; Mack, Taralynn; Heimlich, J Brett; Niroula, Abhishek; Uddin, Md Mesbah; Weinstock, Joshua; Sharber, Brian; Silver, Alexander J; Xu, Yaomin; Savona, Michael; Gibson, Christopher; Lanktree, Matthew B; Rauh, Michael J; Ebert, Benjamin L; Natarajan, Pradeep; Jaiswal, Siddhartha; Bick, Alexander G.

Blood ; 141(18): 2214-2223, 2023 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-36652671

2.

COVID-19 and the Genetics of Inflammation.

Choudhri, Yasmeen; Maslove, David M; Rauh, Michael J.

Crit Care Med ; 51(6): 817-825, 2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-36939259

3.

A Lower Frequency of Spliceosome Mutations Distinguishes Clonal Cytopenias of Undetermined Significance From Low-Risk Myelodysplastic Syndromes, Despite Inherent Similarities in Genomic, Laboratory, and Clinical Features.

Ferrone, Christina K; McNaughton, Amy J M; Rashedi, Iran; Ring, Brooke; Buckstein, Rena; Tsui, Hubert; Rauh, Michael J.

Mod Pathol ; 36(3): 100068, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36788103

4.

Clonal Hematopoiesis of Indeterminate Potential and Kidney Function Decline in the General Population.

Kestenbaum, Bryan; Bick, Alexander G; Vlasschaert, Caitlyn; Rauh, Michael J; Lanktree, Matthew B; Franceschini, Nora; Shoemaker, Moore B; Harris, Raymond C; Psaty, Bruce M; Köttgen, Anna; Natarajan, Pradeep; Robinson-Cohen, Cassianne.

Am J Kidney Dis ; 81(3): 329-335, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36241009

5.

Association of Clonal Hematopoiesis of Indeterminate Potential with Worse Kidney Function and Anemia in Two Cohorts of Patients with Advanced Chronic Kidney Disease.

Vlasschaert, Caitlyn; McNaughton, Amy J M; Chong, Michael; Cook, Elina K; Hopman, Wilma; Kestenbaum, Bryan; Robinson-Cohen, Cassianne; Garland, Jocelyn; Moran, Sarah M; Paré, Guillaume; Clase, Catherine M; Tang, Mila; Levin, Adeera; Holden, Rachel; Rauh, Michael J; Lanktree, Matthew B.

J Am Soc Nephrol ; 33(5): 985-995, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-35197325

6.

Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.

Potus, François; Pauciulo, Michael W; Cook, Elina K; Zhu, Na; Hsieh, Alexander; Welch, Carrie L; Shen, Yufeng; Tian, Lian; Lima, Patricia; Mewburn, Jeffrey; D'Arsigny, Christine L; Lutz, Katie A; Coleman, Anna W; Damico, Rachel; Snetsinger, Brooke; Martin, Ashley Y; Hassoun, Paul M; Nichols, William C; Chung, Wendy K; Rauh, Michael J; Archer, Stephen L.

Circulation ; 141(24): 1986-2000, 2020 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-32192357

7.

Immune Dysregulation and Recurring Mutations in Myelodysplastic Syndromes Pathogenesis.

Matos, Anacélia; Magalhães, Silvia M M; Rauh, Michael J.

Adv Exp Med Biol ; 1326: 1-10, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33385175

8.

Breaking the CH inflammation-expansion cycle.

Rauh, Michael J.

Blood ; 141(8): 815-816, 2023 02 23.

Artigo em Inglês | MEDLINE | ID: mdl-36821185

9.

Age-Associated TET2 Mutations: Common Drivers of Myeloid Dysfunction, Cancer and Cardiovascular Disease.

Ferrone, Christina K; Blydt-Hansen, Mackenzie; Rauh, Michael J.

Int J Mol Sci ; 21(2)2020 Jan 17.

Artigo em Inglês | MEDLINE | ID: mdl-31963585

10.

Interleukin-6 Receptor Polymorphism Attenuates Clonal Hematopoiesis-Mediated Coronary Artery Disease Risk Among 451 180 Individuals in the UK Biobank.

Vlasschaert, Caitlyn; Heimlich, J Brett; Rauh, Michael J; Natarajan, Pradeep; Bick, Alexander G.

Circulation ; 147(4): 358-360, 2023 01 24.

Artigo em Inglês | MEDLINE | ID: mdl-36689568

11.

Longitudinal sequencing of RUNX1 familial platelet disorder: new insights into genetic mechanisms of transformation to myeloid malignancies.

Duarte, Bruno K L; Yamaguti-Hayakawa, Gabriela G; Medina, Samuel S; Siqueira, Lúcia H; Snetsinger, Brooke; Costa, Fernando F; Rauh, Michael J; Ozelo, Margareth C.

Br J Haematol ; 186(5): 724-734, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31124578

12.

A Host of Host Assays: The Clinical Accuracy of Two Host Gene Expression Assays in Acute Infection.

Vlasschaert, Caitlyn; Rauh, Michael J.

Crit Care Med ; 49(10): 1812-1814, 2021 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-34529611

13.

Clonal haematopoiesis, ageing and kidney disease.

Vlasschaert, Caitlyn; Lanktree, Matthew B; Rauh, Michael J; Kelly, Tanika N; Natarajan, Pradeep.

Nat Rev Nephrol ; 20(3): 161-174, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-37884787

14.

Clonal hematopoiesis of indeterminate potential-associated non-small cell lung cancer risk is potentiated by small particulate matter air pollution among non-smokers: a novel somatic variant-environment interaction.

Vlasschaert, Caitlyn; Buttigieg, Marco; Pershad, Yash; Lanktree, Matthew; Aldrich, Melinda C; Rauh, Michael J; Bick, Alexander G.

medRxiv ; 2024 Jan 17.

Artigo em Inglês | MEDLINE | ID: mdl-38293139

15.

Neutrophil-mediated innate immune resistance to bacterial pneumonia is dependent on Tet2 function.

Quin, Candice; DeJong, Erica N; Cook, Elina K; Luo, Yi Zhen; Vlasschaert, Caitlyn; Sadh, Sanathan; McNaughton, Amy Jm; Buttigieg, Marco M; Breznik, Jessica A; Kennedy, Allison E; Zhao, Kevin; Mewburn, Jeffrey; Dunham-Snary, Kimberly J; Hindmarch, Charles Ct; Bick, Alexander G; Archer, Stephen L; Rauh, Michael J; Bowdish, Dawn Me.

J Clin Invest ; 134(11)2024 Apr 04.

Artigo em Inglês | MEDLINE | ID: mdl-38573824

16.

Clonal hematopoiesis of indeterminate potential is associated with acute kidney injury.

Vlasschaert, Caitlyn; Robinson-Cohen, Cassianne; Chen, Jianchun; Akwo, Elvis; Parker, Alyssa C; Silver, Samuel A; Bhatraju, Pavan K; Poisner, Hannah; Cao, Shirong; Jiang, Ming; Wang, Yinqiu; Niu, Aolei; Siew, Edward; Van Amburg, Joseph C; Kramer, Holly J; Kottgen, Anna; Franceschini, Nora; Psaty, Bruce M; Tracy, Russell P; Alonso, Alvaro; Arking, Dan E; Coresh, Josef; Ballantyne, Christie M; Boerwinkle, Eric; Grams, Morgan; Zhang, Ming-Zhi; Kestenbaum, Bryan; Lanktree, Matthew B; Rauh, Michael J; Harris, Raymond C; Bick, Alexander G.

Nat Med ; 30(3): 810-817, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38454125

17.

Clonal Hematopoiesis: Updates and Implications at the Solid Tumor-Immune Interface.

Buttigieg, Marco M; Rauh, Michael J.

JCO Precis Oncol ; 7: e2300132, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37343201

18.

A DNA methylation based measure outperforms circulating CRP as a marker of chronic inflammation and partly reflects the monocytic response to long-term inflammatory exposure: A Canadian Longitudinal Study on Aging analysis.

Verschoor, Chris P; Vlasschaert, Caitlyn; Rauh, Michael J; Paré, Guillaume.

Aging Cell ; 22(7): e13863, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37139638

19.

The Role of Clonal Hematopoiesis of Indeterminant Potential and DNA (Cytosine-5)-Methyltransferase Dysregulation in Pulmonary Arterial Hypertension and Other Cardiovascular Diseases.

Emon, Isaac M; Al-Qazazi, Ruaa; Rauh, Michael J; Archer, Stephen L.

Cells ; 12(21)2023 10 26.

Artigo em Inglês | MEDLINE | ID: mdl-37947606

20.

Expression of TCF3 target genes defines a subclass of diffuse large B-cell lymphoma characterized by up-regulation of MYC target genes and poor clinical outcome following R-CHOP therapy.

Tyryshkin, Kathrin; Moore, Alison; Good, David; Popov, Jesse; Crocker, Susan; Rauh, Michael J; Baetz, Tara; LeBrun, David P.

Leuk Lymphoma ; 64(1): 119-129, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36336953

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