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Ned Tijdschr Geneeskd ; 143(27): 1425-8, 1999 Jul 03.
Artigo em Holandês | MEDLINE | ID: mdl-10422557

RESUMO

OBJECTIVE: To assess the number of possible candidates for paediatric cardiac transplantation and the number of available donors. DESIGN: Retrospective. PATIENTS AND METHODS: The population (date of birth 1 January 1980-31 March 1998) of the Department of Paediatric Cardiology of the Wilhelmina Children's Hospital, Utrecht, the Netherlands, was reviewed for possible candidates for cardiac transplantation and the resulting number of candidates was extrapolated to the entire country. Figures of the transplant co-ordination unit of the University Hospital Utrecht over 1993-1997 were obtained, to estimate the number of available donors. Furthermore, an overview was made of the results of paediatric cardiac transplantations reported in centres around the world. RESULTS: A total number of 15 possible candidates could be selected over the studied period. Extrapolated to the entire country, about 5 candidates each year could be expected. Per year 5 donor hearts of children (< 12 yr) and 11 hearts of adult donors with a low body weight (40-65 kg) have been available for paediatric cardiac transplantation. Worldwide 5- and 10-year survival rates reach 60% and 50%, respectively, morbidity seems low and the quality of life can be considered reasonably good. CONCLUSION: The number of expected recipients corresponds with the number of available donors. Together with the promising results reported in transplant centres around the world, this seems to justify the option of paediatric cardiac transplantation for children with end-stage cardiac disease.


Assuntos
Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos , Insuficiência Cardíaca/terapia , Transplante de Coração/estatística & dados numéricos , Seleção de Pacientes , Doadores de Tecidos/provisão & distribuição , Adolescente , Adulto , Criança , Pré-Escolar , Feminino , Insuficiência Cardíaca/epidemiologia , Transplante de Coração/mortalidade , Humanos , Lactente , Masculino , Países Baixos/epidemiologia , Estudos Retrospectivos , Taxa de Sobrevida
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