A comparison of modelled serum cTnT and cTnI kinetics after 60 min swimming.

Post-exercise elevations of cardiac troponin T (cTnT) and I (cTnI) are often used in isolation but interpreted interchangeably. Research suggests, however, that post-exercise cTn kinetic might differ with each isoform. In this cross-sectional observational study, we collected blood samples before, immediately after (5 minutes), and at 1-, 3-, 6-, 12-, and 24-hour post-exercise in a mixed cohort of 56 participants after a distance-trial of 60 min continuous swimming (age range from 14 to 22, 57.1% female). Cardiac troponin kinetics were modelled using Bayesian mixed-effects models to estimate time to peak (TTP) and peak concentration (PC) for each isoform, while controlling for participants sex, tanner stage and average relative heart rate during the test. Exercise induced an elevation of cTnT and cTnI in 93% and 75% of the participants, respectively. Cardiac troponin T peaked earlier, at 2.9 h (CI: 2.6 - 3.2 h) post-exercise, whereas cTnI peaked later, at 4.5 h (CI: 4.2 - 4.9 h). Peak concentrations for cTnT and cTnI were 2.5 ng/L, CI: 0 - 11.2 ng/L and 2.16 ng/L, CI: 0 - 22.7 ng/L, respectively. Additionally, we did not observe a systematic effect of sex and maturational status mediating cTn responses.

Training volume and amateur cyclists' health: a six-month follow-up from coinciding with a high-demand cycling event.

This study aimed to analyse the longitudinal association of amateur cycling training volume with health by comparing the proximity of participation in a high-demand cycling event. Variations in cycling training volume, behavioural cardiometabolic risk factors, and physical and psychosocial health were examined. Cyclists decreased their training volume by approximately 40% and their total physical activity volumes by approximately 20%, while controls maintained (~5%). A time*group interaction was found for men's physical conditioning, body mass index and anxiety and, independent of gender, for behavioural cardiometabolic risk factors. Variation in cycling training volume was positively correlated with variation in physical conditioning and total physical activity and negatively correlated with variation in body mass index. The high level of cycling training volume developed at the time coinciding with a high demand cycling event predisposes to better physical health and behavioural cardiometabolic risk factors, without negatively affect psychosocial health, compared with six month later.

Effects of Whole-Body Electromyostimulation on Physical Fitness in Postmenopausal Women: A Randomized Controlled Trial.

Whole-body electromyostiulation (WB-EMS) has experienced a boom in recent years, even though its effectiveness is controversial. A sedentary lifestyle is deeply rooted in the European population, mainly in the elderly. This experimental study analyzed the impact of WB-EMS on the physical fitness of postmenopausal women. Thirty-four healthy sedentary women between 55 and 69 years followed an experimental design pre-post-test. Both groups conducted a ten-week aerobic and strength training program. The experimental group overlaid the WB-EMS during exercise. At the end of the intervention, both groups improved upper and lower body strength, lower extremity flexibility, agility, and speed levels (pBonferroni < 0.05). Significant interactions were observed at upper and lower body strength, agility, speed, and cardiovascular endurance (p < 0.05). The WB-EMS group scored better agility than the control group at the end of the intervention (pBonferroni < 0.05) and was the only group that improved cardiovascular endurance. WB-EMS shows a favorable isolate effect on the development of dynamic leg strength, agility, and cardiovascular endurance but did not in dynamic arm strength, gait speed, balance, or flexibility of postmenopausal women.

Amateur endurance cycling practice and adult's physical and psychosocial health: a cross-sectional study of the influence of training volume.

This study aimed to analyse the association between amateur cycling training volume and physical and psychosocial health. A cross-sectional study was developed, via self-reported survey, among 1669 cyclists and 1039 controls, where analysis of variance and hierarchical multiple linear regression test were developed. Independent of gender, high volumes of amateur endurance cycling practice benefited cyclists' body mass index and male cyclists' physical conditioning, while psychosocial health did not differ among the training volume groups. Hierarchical multiple linear regression analysis highlighted the contribution of training volume to lower cyclists' body mass index and better male cyclists' physical conditioning. All cyclist groups presented better physical and psychosocial health than controls. High volumes of amateur endurance cycling training were associated with better physical health without jeopardizing psychosocial health. The practice of amateur endurance cycling, both in low and high volumes, was associated with better physical and psychosocial health compared with inactivity.

The importance of a multidisciplinary team and the conditioning services in elite clubs of roller hockey.

[Purpose] This study describes and compares the conditioning services of the roller hockey teams of the two most important leagues in Spain: the OK Liga and the First Division. [Subjects and Methods] A survey was administered to the people responsible for physical preparation. The response rate was 93%. [Results] 75% of the OK Liga teams have hired someone full time exclusively for training, with a university degree. The percentage was significantly lower in the First Division, at a 43.7%. A low percentage of the physical trainers continued with their academic training, and the consultation of scientific journals. The main deficiencies are associated with the strength training equipment and facilities. In the First Division teams, significant deficiencies were found in most of the variables associated with the training environment. These results show significant deficiencies in the conditioning services offered by the teams to their players, especially in non-professional and lower performance level teams. [Conclusion] Spanish physical trainers should take advantage of advances in scientific knowledge in the area of conditioning by studying Masters and consulting scientific journals. The clubs directors and/or coaches should be aware of the importance of conditioning to improve the training environment. Both aspects would offer a better training and rehabilitation procedure in the club.

Cardiac Biomarker Release after Endurance Exercise in Male and Female Adults and Adolescents.

OBJECTIVES: To compare the responses of high-sensitivity cardiac troponin T (hs-cTnT) and NH2-terminal probrain natriuretic peptide (NT-proBNP) after 60 minutes of swimming in male and female adults and adolescents with different pubertal status. STUDY DESIGN: Adolescent swimmers (25 male and 25 female) and adult swimmers (7 male and 9 female) participated in a 60-minute maximal swimming test with serial assessment of hs-cTnT and NT-proBNP at rest, immediately postexercise, and at 1, 3, 6, 12, and 24 hours postexercise. Adolescents were classified according to pubertal status: Tanner stages 3 (n = 14), 4 (n = 22), and 5 (n = 14). RESULTS: Exercise resulted in an increase in both biomarkers. hs-cTnT responses to exercise were similar in adolescents with different pubertal status and adults, although there was substantial individual variability in peak hs-cTnT, with the upper reference limit exceeding in 62% of the participants. Postexercise kinetics for hs-cTnT were largely consistent across all groups with a return to near baseline levels 24 hours postexercise. The male participants showed higher values of hs-cTnT at baseline and postexercise. All groups had similar NT-proBNP responses to acute exercise and recovery. One swimmer exceeded the upper reference limit for NT-proBNP. CONCLUSIONS: An exercise-associated increase in hs-cTnT and NT-proBNP occurred in response to a 60-minute maximal swimming test that was independent of pubertal status/adolescent vs adults. The present data also suggests that baseline and postexercise hs-cTnT values are higher in male compared with female, with no sex differences in NT-proBNP values.

Cardiac troponin I release after a basketball match in elite, amateur and junior players.

BACKGROUND: Available scientific data related to cardiac troponin I (cTnI) release after intermittent exercise is limited. It is also of interest to determine what personal or environmental factors mediate the exercise-induced release of cTnI. This study had two objectives: 1) to examine the individual release of cTnI to a basketball match; and 2) to establish the influence of athlete status as well as biological age on cTnI release. METHODS: Thirty-six basketball players (12 adult elite [PBA]: 27.3±4.1 years, 12 adult amateur [ABA]: 29.6±2.9 years, and 12 junior elite [JBA]: 16.6±0.9 years) participated in a simulated basketball match with serial assessment of cTnI at rest, immediately post- and at 1, 3, 6, 12, and 24 h post-exercise. RESULTS: The basketball match increased cTnI levels (pre: median [range]; 0.006 [0.001-0.026]; peak post: 0.024 [0.004-0.244] µg/L; p=0.000), with substantial individual variability in peak values. PBA and JBA players showed higher baseline and post-exercise cTnI values than ABA (all p<0.05). Peak cTnI exceeded the upper reference limit (URL) in the 26% of players (3 PBA; 6 JBA). CONCLUSIONS: The current results suggest that intermittent exercise can promote the appearance of cTnI and that this is potentially mediated by athlete status.

Impact of an endurance training program on exercise-induced cardiac biomarker release.

We evaluated the influence of a 14-wk endurance running program on the exercise-induced release of high-sensitivity cardiac troponin T (hs-cTnT) and NH2-terminal pro-brain natriuretic peptide (NT-proBNP). Fifty-eight untrained participants were randomized to supervised endurance exercise (14 wk, 3-4 days/wk, 120-240 min/wk, 65-85% of maximum heart rate) or a control group. At baseline and after the training program, hs-cTnT and NT-proBNP were assessed before and 5 min, 1 h, 3 h, 6 h, 12 h, and 24 h after a 60-min maximal running test. Before training, hs-cTnT was significantly elevated in both groups with acute exercise (P < 0.0001) with no between-group differences. There was considerable heterogeneity in peak hs-cTnT concentration with the upper reference limit exceeded in 71% of the exercise tests. After training, both baseline and postexercise hs-cTnT were significantly higher compared with pretraining and the response of the control group (P = 0.008). Acute exercise led to a small but significant increase in NT-proBNP, but this was not mediated by training (P = 0.121). In summary, a controlled endurance training intervention resulted in higher pre- and postexercise values of hs-cTnT with no changes in NT-proBNP.

Individual variability of high-sensitivity cardiac troponin levels after aerobic exercise is not mediated by exercise mode.

We compared the response of high-sensitivity cardiac troponin T (hs-cTnT) after 60 min of swimming, running and cycling in well-trained triathletes. The maximal increase in hs-cTnT was similar in all exercise bouts (swimming 453%, cycling 349% and running 471%) although there was substantial individual variability in peak hs-cTnT. The post-exercise kinetics for hs-cTnT was consistent. The change in hs-cTnT was correlated between trials. In all trials, hs-cTnT had largely returned to baseline levels 24 h post-exercise. In summary, an increase in hs-cTnT was apparent in all triathletes independent of exercise mode and despite variable peak data the consistent kinetics over 24 h post-exercise would suggest this represents a physiological phenomenon.

Global research trends on cardiac troponin and physical activity among pediatric populations: a bibliometric analysis and science mapping study.

Background: Cardiac troponin (cTn) is a reliable marker for evaluating myocardial damage. cTn is a very specific protein involved in myocardial injury, and it is a key factor in the diagnosis of coronary syndromes. Bibliometric analysis was applied in the present work, with the main goal of evaluating global research on the topic of cardiac troponin in pediatric populations. Methods: Publications about cardiac troponin and physical activity in pediatric populations were retrieved from the Social Sciences Citation Index (SSCI) and the Science Citation Index Expanded (SCIE) of the Web of Science Core Collection, and they were then analyzed. The study was able to identify the key bibliometric indicators, such as publications, keywords, authors, countries, institutions, and journals. For the analysis, VOSviewer, R-based Bibliometrix (4.2.2), and MapChart were used. Results: Initially, 98 documents were identified; however, once inclusion and exclusion criteria were applied, the number of documents decreased to 88. The search yielded 79 original research articles and 9 reviews, almost all of which were published in the past 2 decades. The total number of citations (Nc) of the retrieved publications was 1,468, and the average number of citations per article (Na) was 16.68. In general, 508 authors were found to have participated in research about troponin; they were associated with 256 institutions, and their work was published in 65 different journals from around the world. The authors hailed from 30 countries and/or regions. The year 2022 was the most productive year for the publication of the selected documents. The bibliometric analysis provided information regarding levels of cooperation among authors and institutions. In fact, China, the United States, and England were the most productive nations, and the journal with the greatest number of publications on the topic was Pediatric Cardiology. Summary: The number of publications and the trend line show that research on this topic has not yet reached a stage of maturity. There are referent investigators, countries, and institutions that have laid the foundations for subsequent studies on the analyzed topic.

Cardiac Troponin Release after Exercise in Healthy Young Athletes: A Systematic Review.

Cardiac troponin (cTn) is a recognized marker used to assess damage to the heart muscle. Actual research has indicated that the levels of cTn increase after doing exercise in individuals who are in good health, and this is believed to be a result of a normal cellular process rather than a pathological one. The main goal of this study was to investigate the evidence of a postexercise release of cTn in child and adolescent athletes (6-17.9 years old) of different ages, sex, and sports disciplines. The Web of Science, MEDLINE, and Scopus databases were used to conduct the research up to March 2023. Three hundred and twenty-eight records were identified from the databases, however, only twenty-three studies were included in the review after being screened and quality-assessed by two independent authors. The gender, age of the participants, maturational status, and training level of the participants, the timing of sample collection, the exercise modality, and the number of participants with values above the cut-off reference were the data analyzed. Males, older young people, and individual sports seemed to have higher levels of serum cTn after practice exercise. Different methodologies, analyzers, and cut-off reference values make it difficult to compare the data among studies.

Sleep quality is mediated by physical activity level in adolescents.

BACKGROUND: Sleep is essential for the adolescent's health and well-being. Despite existing evidence of the positive relationship between physical activity and quality of sleep, some other factors could mediate this association. The purpose of the present study was to clarify the interaction between the level of physical activity and sleep in adolescents depending on their gender. METHODS: A total of 12,459 subjects 11 to 19 years old (5073 male and 5016 female) reported data regarding their quality of sleep and their level of physical activity. RESULTS: Better quality of sleep was reported by males regardless of the level of physical activity (d=0.25, P<0.001). Better quality of sleep was reported by active subjects (P<0.05), and it improved in both sexes as the level of physical activity was higher (P<0.001). CONCLUSIONS: Male adolescents have better sleep quality than females regardless of their competitive level. The higher the adolescents' physical activity level the higher the quality of sleep.

The Top 100 Most Cited Scientific Papers in the Public, Environmental & Occupational Health Category of Web of Science: A Bibliometric and Visualized Analysis.

(1) Background: The main basis for the public recognition of the merits of scientists has always been the system of scientific publications and citations. Our goal is to identify and analyze the most cited articles in the Public, Environmental & Occupational Health category. (2) Methods: We searched the Web of Science for all articles published in the "Public, Environmental & Occupational Health" category up to March 2022 and selected the 100 most cited articles. We recorded the number of citations, the journal, the year of publication, quartile, impact factor, institution, country, authors, topic, type of publication and collaborations. (3) Results: 926,665 documents were analyzed. The top 100 had 401,620 citations. The journal with the most articles was the Journal of Clinical Epidemiology and the one with the highest number of citations was Medical Care. The year with the highest number of articles in the top 100 was 1998. The country with the highest percentage of publications was the USA and the most productive institution was Harvard. The most frequent keywords were bias, quality, and extension. The largest collaboration node was between the USA, Canada, Germany, Spain, Australia, France, and Sweden. (4) Conclusions: This bibliometric study on Public, Environmental & Occupational Health provides valuable information not only to identify topics of interest in the analyzed category, but also to identify the differences in the topics they study.

Exercise-Induced Release of Cardiac Troponins in Adolescent vs. Adult Swimmers.

To examine the exercise-induced release of cardiac troponin T (cTnT) in adolescent and adult swimmers. Thirty-two trained male (18 adolescents, 14 adults) swam at maximal pace in a 45 min distance trial, and blood samples were drawn before, immediately and 3 h after exercise for subsequent cTnT analysis and comparison. Having comparable training experience and baseline values of cTnT (p = 0.78 and p = 0.13), adults exercised at lower absolute and relative intensity (p < 0.001 and p < 0.001, respectively), but presented higher immediate cTnT after exercise than adolescents (p < 0.001). Despite that, peak concentrations were observed at 3 h post exercise and peak elevations were comparable between groups (p = 0.074). Fourteen (44%) apparently healthy subjects exceeded the cutoff value for myocardial infarction (MI). Adolescents presented a delayed elevation of cTnT compared with adults, but achieved similar peak values.

Influence of maturational status in the exercise-induced release of cardiac troponin T in healthy young swimmers.

OBJECTIVES: To determine the influence of maturational status on the release of cardiac troponin T (cTnT) induced by a bout of 30min, high-intensity, continuous exercise. DESIGN: Quasi-experimental, cross-sectional study. METHODS: Seventy male, young, well trained swimmers (age range 7-18 years, training experience 1-11 years) were classified by maturational stages: Tanner stage I (n=14), II (n=15), III (n=15), IV (n=13), and V (n=13). Participants underwent a distance-trial of 30min continuous swimming, and cTnT was measured before, immediately after and 3h after exercise. Changes in cTnT over time were compared among groups, and associated with exercise load. RESULTS: Basal cTnT was higher in Tanner-V (3.8-8.1ng/L) compared with I (1.5-5.5ng/L, p<0.001), II (1.5-4.5ng/L, p<0.001) and III (1.5-6.8ng/L, p=0.003), and in IV (1.5-6.3ng/L) compared with II (p=0.036). Maximal elevations of cTnT from baseline were notable (p<0.001) and comparable among maturational stages (p=0.078). The upper reference limit for myocardial injury was exceeded in 35.7% of the participants, without differences among groups (p=0.18). Baseline cTnT correlated with participant characteristics, and maximal cTnT elevations from baseline with exercise internal load (%HRpeak, rs=0.34, p= 0.003; %HRmean, rs=0.28, p=0.02). CONCLUSIONS: Maturational status influences positively absolute pre- and post-exercise cTnT but not its elevation after a bout of 30min, high-intensity, continuous exercise.

Impact of Whole Body Electromyostimulation on Velocity, Power and Body Composition in Postmenopausal Women: A Randomized Controlled Trial.

Menopause is associated with losses in strength and power along with weight and fat mass gains, which may result from menopause-related hormonal changes, aging-associated diseases, and decreased physical activity time. The objective of this study is to analyze if whole-body electromyostimulation (WB-EMS) is suitable for the prevention and treatment of postmenopausal physical deterioration. Thirty-four healthy sedentary women between 55 and 69 years followed an experimental design pre-post test. Both groups conducted 10 weeks of aerobic and strength training program. The experimental group conducted the training with superimposed WB-EMS during exercise. At the end of the intervention, the experimental group obtained better power (Squat: mean difference (MD) = 38.69 W [1.75,75.62], d = 0.81; Bench press: MD = 25.64 W [17.48, 33.82], d = 2.39) and velocity (Squat: MD = 0.04 m·s-1 [0.01, 0.08], d = 0.98; Bench press: MD = 0.10 m·s-1 [0.06, 0.14], d = 1.90) score improvements than the other group (pBonferroni < 0.05). Furthermore, trivial to small effects were found in the body composition of the participants of both groups (p > 0.050). WB-EMS showed a favorable isolated effect on the development of power and velocity, but it induced negligible effects on the body composition of postmenopausal women.

Cardiac Troponin T Release after Football 7 in Healthy Children and Adults.

The objective of this study was to compare the release of cardiac troponin T (cTnT) after a football 7 match between two cohorts of children and adult players. Thirty-six male football players (children = 24, adult = 12) played a football 7 match, and cTnT was measured before, and 3 h after exercise. Concentrations of cTnT were compared between groups and time, and correlated with participants' characteristics, as well as internal and external exercise load. Cardiac troponin T was elevated in all participants (p < 0.001), and exceeded the upper reference limit for myocardial infarction in 25 (~70%) of them. Baseline concentrations were higher in adults (p < 0.001), but the elevation of cTnT was comparable between the groups (p = 0.37). Age (p < 0.001), body mass (p = 0.001) and height (p < 0.001), and training experience (p = 0.001) were associated to baseline cTnT values, while distance (p < 0.001), mean speed (p < 0.001), and peak (p = 0.013) and mean (p = 0.016) heart rate were associated to the elevation of cTnT. The present study suggests that a football 7 match evoked elevations of cTnT during the subsequent hours in healthy players regardless of their age. However, adults might present higher resting values of cTnT than children. In addition, results suggest that the exercise-induced elevations of cTnT might be mediated by exercise load but not participant characteristics.

Exercise Addiction and Its Relationship with Health Outcomes in Indoor Cycling Practitioners in Fitness Centers.

We studied the prevalence and possible association between exercise addiction and health in indoor cycling practitioners. In 1014 (492 women) adult indoor cyclists and 926 (597 women) controls with low levels of physical activity according to the short form of the International Physical Activity Questionnaire, we examined the risk of exercise addiction according to the Exercise Addiction Inventory and several health outcomes through a web-based experiment. The prevalence of a high risk of exercise addiction in cyclists was 13.3%, and it was higher in men than in women (16.5% vs. 10.0%, p = 0.002). Women cyclists with a high risk of exercise addiction had higher levels of physical activity (p < 0.001; effect size = -0.62, 95% CI: (-0.91, -0.32)) and anxiety symptom severity (p = 0.001; Effect Size (ES) = -0.59 (-0.89, -0.30)) than those with a low risk. For both sexes, cyclists with a low risk of exercise addiction had better social function, emotional role, and anxiety symptom severity compared with the controls (all p < 0.002; ES ranged from 0.25 to 0.47). Higher anxiety symptom severity and cardiorespiratory fitness were the main determinants of exercise addiction in cyclists (both p < 0.001). Our data suggest the importance of considering exercise addiction in indoor cyclists.

A profile of the resistance training practices of elite Spanish club teams.

This study describes the results of a survey of the resistance training practices of the following Spanish sports teams: soccer and basketball professional leagues, and top-division leagues for handball, volleyball, indoor soccer, and field hockey. The response rate was 81.8% (77 of 94). This survey examines (a) strength and conditioning (S&C) coach profiles, (b) resistance training exercises, (c) resistance training load, (d) repetition velocity, and (e) training leading to muscle failure. The results indicate that 80.5% of coaches held a university degree, with 22% holding a master's degrees, 40% held National Federation certification, and none held Strength and Conditioning Specialist certification. Respondents relied on nonscientific sources of information to develop their conditioning programs. Fifty-eight percent of the S&C coaches were hired full time, with 18% performing the duties of a first trainer. Many S&C coaches did not use weightlifting (54%), full squat (51%), load squat jump (35%), or bench press throw (100%) exercises. Thirty-eight percent of respondents did not control the load intensity or did not use a load of 50-90% of 1 repetition maximum. For these load intensities, 70% did not perform the combination of maximum repetition velocity and nonmuscular failure. More significant deficiencies in the fundamental principles of resistance training were observed in indoor soccer, soccer, field hockey, and among lower performing handball and basketball teams. These results indicate that the profile of the S&C coaches in the Spanish teams is insufficient for an optimal application of resistance training. Spanish S&C coaches should therefore take advantage of advances made through scientific research in the area of strength and conditioning by acquiring master's degrees and specific certificates and consulting peer-reviewer journals.

Effect of Training Load on Post-Exercise Cardiac Troponin T Elevations in Young Soccer Players.

Training load (TL) metrics are usually assessed to estimate the individual, physiological and psychological, acute, and adaptive responses to training. Cardiac troponins (cTn) reflect myocardial damage and are routinely analyzed for the clinical diagnosis of myocardial injury. The association between TL and post-exercise cTn elevations is scarcely investigated in young athletes, especially after playing common team sports such as soccer. The objective of this study was to assess the relationship between TL measurements during a small-sided soccer game and the subsequent increase in cTn in young players. Twenty male soccer players (age 11.9 ± 2 years, height 151 ± 13 cm, weight 43 ± 13 kg) were monitored during a 5 × 5 small-sided game and had blood samples drawn before, immediately after, and 3 h after exercise for a posterior analysis of high-sensitivity cardiac troponin T (hs-cTnT). Internal, external, and mixed metrics of TL were obtained from the rating of perceived exertion (RPE), heart rate (HR), and GPS player tracking. The results show that the concentration of hs-cTnT peaked at 3 h post-exercise in all participants. The magnitude of hs-cTnT elevation was mainly explained by the exercise duration in the maximal heart rate zone (Maximum Probability of Effect (MPE) = 92.5%), time in the high-speed zone (MPE = 90.4 %), and distance in the high-speed zone (MPE = 90.45%). Our results support the idea that common metrics of TL in soccer, easily obtained using player tracking systems, are strongly associated with the release of hs-cTnT in children and adolescents.