RESUMO
The filling material of endomethasone Spad, N2, AH26, Diaket, Iod paste which are used in clinics often are evaluated from the point of view of their antibacterial effects to the microorganisms which are isolated from root canals. In the study, streptococcus were defined as the most often producing microorganisms in the canals. It was observed that, on the producing microorganisms, the most effective filling materials were spad and N2, following these were AH26, Diaket the less effective filling materials were endomenthasone and iod paste.
Assuntos
Administração Tópica , Bactérias/efeitos dos fármacos , Cavidade Pulpar/microbiologia , Resinas Epóxi , Hidrocortisona , Materiais Restauradores do Canal Radicular/farmacologia , Anti-Inflamatórios/farmacologia , Bismuto/farmacologia , Dexametasona/farmacologia , Combinação de Medicamentos , Eugenol/farmacologia , Formaldeído/farmacologia , Humanos , Metenamina/farmacologia , Polímeros/farmacologia , Polivinil/farmacologia , Resorcinóis/farmacologia , Prata/farmacologia , Streptococcus/efeitos dos fármacos , Timol/análogos & derivados , Timol/farmacologia , Titânio/farmacologia , Óxido de Zinco/farmacologiaRESUMO
The aim of the study was to determine the correlation of the antibacterial substance nitric oxide (NO) with dental caries in vivo. Salivary and dental plaque NO concentrations were analyzed by the Griess method in 11 subjects with high DMFT index and simplified oral hygiene index (OHI-S), 11 with low DMFT and OHI-S. Subjects with high DMFT and OHI-S had significantly higher NO concentrations in saliva (71.5 microM) and plaque (83.5 microM) than those with low DMFT and OHI-S (33.2 and 61.1 microM in saliva and plaque, respectively). Plaque NO concentrations were significantly higher than in saliva in both groups. NO production might be a host defense mechanism when dental caries increases or oral hygiene deteriorates.