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Artigo em Inglês | MEDLINE | ID: mdl-57194

RESUMO

Complement consumption induced by Fab' fragments of rabbit IgG, irrespectively of their state of aggregation, requires the presence of homologous rabbit IgG. Up to a certain concentration of Fab' fragment, the amount of complement fixed is a linear function of the Fab' fragment dose, but further raising of the Fab'-fragment concentration does not result in complete complement consumption in the sample. The interaction between Fab' fragment and IgG is not strictly species specific.


Assuntos
Testes de Fixação de Complemento , Fragmentos Fab das Imunoglobulinas , gama-Globulinas/metabolismo , Animais , Cobaias , Coelhos , Especificidade da Espécie
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