RESUMO
BACKGROUND: Ocular rosacea is an underdiagnosed form of rosacea that may occur without typical cutaneous signs of rosacea. Manifestations include blepharitis, lid margin telangiectasias, and scleritis. A systematic comparison of treatment options for ocular rosacea in children is lacking. METHODS: A systematic review was conducted according to the PRISMA guidelines on treatment for pediatric ocular rosacea. RESULTS: Eleven articles were included, representing 135 patients with a mean age of 5â¯years, of whom 69% (nâ¯=â¯75/108) were female. 55% (nâ¯=â¯55/99) exhibited ocular symptoms prior to cutaneous symptoms. Most patients (83%, nâ¯=â¯34/41) experienced a delay in diagnosis (mean 27â¯months, range 2-120â¯months). Doxycycline was the most frequently reported treatment (25%, nâ¯=â¯33/135). A complete response was achieved in 33% of patients treated with doxycycline (nâ¯=â¯10/30), while 53% (nâ¯=â¯16/30) achieved a partial response. Erythromycin was used in 20% of cases (nâ¯=â¯26/135), with a complete response in 58% (nâ¯=â¯15/26) and partial response in 42% (nâ¯=â¯11/26). Metronidazole was used in 14% of patients (nâ¯=â¯19/135), with a complete response being reported in 79% (nâ¯=â¯15/19) and partial response in 21% (nâ¯=â¯4/19). CONCLUSION: Systemic antibiotics, led by doxycycline, were the most commonly reported treatment modalities for pediatric ocular rosacea. Increased awareness of ocular rosacea in this population is crucial for earlier diagnosis.