Pesquisa | BVS Educação Profissional em Saúde

1.

Affirming NIH's commitment to addressing structural racism in the biomedical research enterprise.

Collins, Francis S; Adams, Amy Bany; Aklin, Courtney; Archer, Trevor K; Bernard, Marie A; Boone, Ericka; Burklow, John; Evans, Michele K; Jackson, Sadhana; Johnson, Alfred C; Lorsch, Jon; Lowden, Mia Rochelle; Nápoles, Anna María; Ordóñez, Anna E; Rivers, Robert; Rucker, Victoria; Schwetz, Tara; Segre, Julia A; Tabak, Lawrence A; Hooper, Monica Webb; Wolinetz, Carrie.

Cell ; 184(12): 3075-3079, 2021 06 10.

Artigo em Inglês | MEDLINE | ID: mdl-34115967

2.

Quantitative mapping of the in vivo O-GalNAc glycoproteome in mouse tissues identifies GalNAc-T2 O-glycosites in metabolic disorder.

Yang, Weiming; Tian, E; Chernish, Aliona; McCluggage, Peggy; Dalal, Kruti; Lara, Alexander; Ten Hagen, Kelly G; Tabak, Lawrence A.

Proc Natl Acad Sci U S A ; 120(43): e2303703120, 2023 Oct 24.

Artigo em Inglês | MEDLINE | ID: mdl-37862385

3.

Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation.

Zhang, Liping; Mann, Matthew; Syed, Zulfeqhar A; Reynolds, Hayley M; Tian, E; Samara, Nadine L; Zeldin, Darryl C; Tabak, Lawrence A; Ten Hagen, Kelly G.

Proc Natl Acad Sci U S A ; 118(47)2021 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-34732583

4.

The structure of the colorectal cancer-associated enzyme GalNAc-T12 reveals how nonconserved residues dictate its function.

Fernandez, Amy J; Daniel, Earnest James Paul; Mahajan, Sai Pooja; Gray, Jeffrey J; Gerken, Thomas A; Tabak, Lawrence A; Samara, Nadine L.

Proc Natl Acad Sci U S A ; 116(41): 20404-20410, 2019 10 08.

Artigo em Inglês | MEDLINE | ID: mdl-31548401

5.

Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding.

Tian, E; Wang, Shengjun; Zhang, Liping; Zhang, Ying; Malicdan, May C; Mao, Yang; Christoffersen, Christina; Tabak, Lawrence A; Schjoldager, Katrine T; Ten Hagen, Kelly G.

Proc Natl Acad Sci U S A ; 116(50): 25196-25202, 2019 12 10.

Artigo em Inglês | MEDLINE | ID: mdl-31740596

6.

Differential splicing of the lectin domain of an O-glycosyltransferase modulates both peptide and glycopeptide preferences.

May, Carolyn; Ji, Suena; Syed, Zulfeqhar A; Revoredo, Leslie; Paul Daniel, Earnest James; Gerken, Thomas A; Tabak, Lawrence A; Samara, Nadine L; Ten Hagen, Kelly G.

J Biol Chem ; 295(35): 12525-12536, 2020 08 28.

Artigo em Inglês | MEDLINE | ID: mdl-32669364

7.

Testing for Fentanyl - Urgent Need for Practice-Relevant and Public Health Research.

Volkow, Nora D; Califf, Robert M; Sokolowska, Marta; Tabak, Lawrence A; Compton, Wilson M.

N Engl J Med ; 388(24): 2214-2217, 2023 Jun 15.

Artigo em Inglês | MEDLINE | ID: mdl-37306505

8.

Improved online LC-MS/MS identification of O-glycosites by EThcD fragmentation, chemoenzymatic reaction, and SPE enrichment.

Yang, Shuang; Wang, Yan; Mann, Matthew; Wang, Qiong; Tian, E; Zhang, Liping; Cipollo, John F; Ten Hagen, Kelly G; Tabak, Lawrence A.

Glycoconj J ; 38(2): 145-156, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33068214

9.

Members of the GalNAc-T family of enzymes utilize distinct Golgi localization mechanisms.

Becker, Jessica L; Tran, Duy T; Tabak, Lawrence A.

Glycobiology ; 28(11): 841-848, 2018 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-30084948

10.

Transforming Clinical Research to Meet Health Challenges.

Wolinetz, Carrie D; Tabak, Lawrence A.

JAMA ; 329(20): 1740-1741, 2023 05 23.

Artigo em Inglês | MEDLINE | ID: mdl-37115557

11.

Research Opportunities to Address Nutrition Insecurity and Disparities.

Zenk, Shannon N; Tabak, Lawrence A; Pérez-Stable, Eliseo J.

JAMA ; 327(20): 1953-1954, 2022 05 24.

Artigo em Inglês | MEDLINE | ID: mdl-35486390

12.

Mucin-type O-glycosylation is controlled by short- and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family.

Revoredo, Leslie; Wang, Shengjun; Bennett, Eric Paul; Clausen, Henrik; Moremen, Kelley W; Jarvis, Donald L; Ten Hagen, Kelly G; Tabak, Lawrence A; Gerken, Thomas A.

Glycobiology ; 26(4): 360-76, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26610890

13.

Policy: NIH plans to enhance reproducibility.

Collins, Francis S; Tabak, Lawrence A.

Nature ; 505(7485): 612-3, 2014 Jan 30.

Artigo em Inglês | MEDLINE | ID: mdl-24482835

14.

The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation.

Gerken, Thomas A; Revoredo, Leslie; Thome, Joseph J C; Tabak, Lawrence A; Vester-Christensen, Malene Bech; Clausen, Henrik; Gahlay, Gagandeep K; Jarvis, Donald L; Johnson, Roy W; Moniz, Heather A; Moremen, Kelley.

J Biol Chem ; 288(27): 19900-14, 2013 Jul 05.

Artigo em Inglês | MEDLINE | ID: mdl-23689369

15.

A computational and experimental study of O-glycosylation. Catalysis by human UDP-GalNAc polypeptide:GalNAc transferase-T2.

Gómez, Hansel; Rojas, Raúl; Patel, Divya; Tabak, Lawrence A; Lluch, José M; Masgrau, Laura.

Org Biomol Chem ; 12(17): 2645-55, 2014 May 07.

Artigo em Inglês | MEDLINE | ID: mdl-24643241

16.

The role of mucin-type O-glycans in eukaryotic development.

Tabak, Lawrence A.

Semin Cell Dev Biol ; 21(6): 616-21, 2010 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-20144722

17.

Emerging paradigms for the initiation of mucin-type protein O-glycosylation by the polypeptide GalNAc transferase family of glycosyltransferases.

Gerken, Thomas A; Jamison, Oliver; Perrine, Cynthia L; Collette, Jeremy C; Moinova, Helen; Ravi, Lakshmeswari; Markowitz, Sanford D; Shen, Wei; Patel, Himatkumar; Tabak, Lawrence A.

J Biol Chem ; 286(16): 14493-507, 2011 Apr 22.

Artigo em Inglês | MEDLINE | ID: mdl-21349845

18.

Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family.

Bennett, Eric P; Mandel, Ulla; Clausen, Henrik; Gerken, Thomas A; Fritz, Timothy A; Tabak, Lawrence A.

Glycobiology ; 22(6): 736-56, 2012 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-22183981

19.

UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree.

Raman, Jayalakshmi; Guan, Yu; Perrine, Cynthia L; Gerken, Thomas A; Tabak, Lawrence A.

Glycobiology ; 22(6): 768-77, 2012 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-22186971

20.

A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis.

Verzijl, Cristy R C; Oldoni, Federico; Loaiza, Natalia; Wolters, Justina C; Rimbert, Antoine; Tian, E; Yang, Weiming; Struik, Dicky; Smit, Marieke; Kloosterhuis, Niels J; Fernandez, Amy J; Samara, Nadine L; Ten Hagen, Kelly G; Dalal, Kruti; Chernish, Aliona; McCluggage, Peggy; Tabak, Lawrence A; Jonker, Johan W; Kuivenhoven, Jan Albert.

Mol Metab ; 60: 101472, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35304331

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