Scanning electron microscopic ultrastructural alterations of the pulmonary alveolus in experimental drowning.

Scanning electron microscopic structural and ultrastructural alterations of alveolar wall in experimental drowning are described. The results obtained confirm the literature's data. Peculiar microlesions affecting Type I alveolar cells, the basement membrane, and sometimes the capillary endothelium could also be observed. Finally, Type II alveolar cells show alterations which could be related with a possible direct action of the drowning liquid.

[Monitoring of phenobarbital use during the neonatal period by means of urinalysis]. / Monitoraggio del fenobarbital in epoca neonatale mediante dosaggio su urine.

Monitoring of blood barbiturate level was performed in 32 term newborns, who received 6 mg/Kg/die phenobarbital (PB), by assaying blood and urine samples. Cases were grouped according to duration of treatment which varied following multiples of 12 hours from 16 to 100 hours. Serum and urine PB assay was conducted through immunological percentage nephelometric inhibition. Plasma and urine PB levels within each group were significantly correlated (r = 0.8826; p less than 0.001), indicating that, if PB treatment is given without variations in dosage and if diuresis is not impaired, blood barbiturate level may be monitored through urine assays.

[Influence of salivary Ph on the correlation between salivary and plasma levels of phenobarbital in the neonatal period]. / Influenza del pH salivare sulla correlazione tra tassi salivari e plasmatici del fenobarbital in epoca neonatale.

The influence of salivary pH on the estimate of blood barbiturates obtained by measuring phenobarbital on saliva at newborn age.