Osseointegration of chemically modified sandblasted and acid-etched titanium implant surface in diabetic rats: a histological and scanning electron microscopy study.

INTRODUCTION: The aim of this study is to assess the osseointegration of different dental implants surfaces in diabetic rats. MATERIALS AND METHODS: In this study, were used 56 male Wistar rats, average weight of 300-350 g. Diabetes was induced by a single intraperitoneal injection of Streptozotocin. The glucose levels and weight of rats were periodically evaluated. After the diabetes mellitus is confirmed, the sandblasted, large-grit, acid-etched (SLA) and SLActive endosseous dental implants (TAG dental implants, TAG Medical, Israel), made of titanium alloy, Ti-6Al-4V, 1 mm diameter and 3 mm in length were inserted in the distal metaphysis of the left femur. RESULTS: Diabetic rats have naturally lower number of bone cells and bone-implant contact (BIC%) than healthy rats when using the SLA implant, but when using SLActive implant, diabetic and healthy rats have the same numbers. CONCLUSIONS: The use of the SLActive surface resulted in positive effects in healthy and especially in diabetic animals, which demonstrate that could improve the osseointegration progress in humans with diabetes.

Hemangioma of the parotid gland: case report.

Hemangiomas account for half of the parotid gland tumors occurring in children. After a rapid increase in the first months of life, some of them gradually regress (until complete disappearance) in a period of several years. Hemangiomas that do not regress over time, grow in size (possibly within a short period of time) or develop complications such as intralesional acute bleeding or thrombosis require aggressive therapy: intralesional corticosteroid injection, sclerotherapy. radiation therapy, laser photocoagulation. embolization, or surgical removal. We present the case of a 12-year-old boy with hemangioma of the left parotid gland diagnosed by CT scan, angio-CT with 3D reconstruction and angiography successfully treated by superselective intraarterial embolization with acrylic glue followed after 4 days by left superficial parotidectomy with facial nerve preservation.

[Malherbe's calcifying epithelioma--comment on two clinical cases]. / Epiteliom calcificat malherbe--observatii pe marginea a doua cazuri clinice.

Malherbe's calcifying epithelioma (also called trichomatricoma, pilomatrixoma or pilomatricoma) is an uncommon benign cutaneous tumor, which takes the form of a solitary, firm, asymptomatic, slowly growing nodule, developed subcutaneously on the face, neck, or proximal upper extremity. With an incidence of 1/800-1000 cutaneous tumors, pilomatricoma is more common in the first two decades of life, predominantly affecting the women. Multiple locations and associations between this entity and other diseases such as Steinert's myotonic dystrophy or Gardner syndrome have been described in the literature. The clinical diagnosis is often difficult, most cases being mistaken as sebaceous cysts. The treatment of choice is surgical excision. Incomplete surgical excision can be followed by local recurrence because most lesions are poorly defined; therefore, patients should be monitored after surgical excision to prevent this from happening. We present two cases admitted in 2010 and 2011 to the Iasi Department of Oral and Maxillo-Facial Surgery: a 55-year-old female patient with a Malherbe's calcifying epithelioma located in the left temporal region, and a 51-year-old female patient with the same disease but located in the left masseter region.

[Dermoid cyst of the parotid gland]. / Chistul dermoid al glandei parotide.

Dermoid cyst of the parotid gland is a rare clinical entity. Definitive clinical diagnosis is often difficult to determine preoperatively because of the lack of pathognomonic features. The most frequent location of a parotid dermoid cyst is a triangular area lying above the pinna. Imaging studies do not definitely diagnose a parotid dermoid cyst. Although parotid dermoid cyst is (generally) well-encapsulated, complete removal of the cyst wall is not sufficient to cure it, so it is mandatory to perform careful excision of the cyst by parotidectomy, in terms of preserving facial nerve integrity. Histopathology of the parotid gland tumor removed by parotidectomy makes a diagnosis of certainty, by revealing a cyst wall with keratinization of the squamous epithelium and the presence of skin annexes (hair follicles, sweat glands, sebaceous glands). We present a rare case of parotid dermoid cyst in a 21-year-old male patient with symptoms and imaging rather suggestive of arch I branchial cyst and a brief review of data in the medical literature of the last 20 years.

[Generalized gingival enlargement--early clinic manifestation in acute leukemia. Case report]. / Hiperplazia gingivala generalizata-- manifestare clinica precoce în leucemia acuta. Prezentare de caz.

Leukemia is a hematological disorder arises from a hematopoietic stem cell characterized by a disordered differentiation and proliferation of neoplastic cells. Rapidly forming generalized gingival hyperplasia is usually the first sign of this disease (especially in acute forms). This case report describes a 54-year-old female who presented rapid gingival enlargement in only three weeks time, heralding the presence of acute monocytic leukemia (AML-FAB M5). The patient was immediately referred for hematologic management, but died five weeks later. Dentists and generalists should always be on guard to observe any oral manifestations that may lead to the early diagnostic of systemic diseases.

[Lipomas of the oral cavity--a retrospective study]. / Lipoamele cavitatii orale--studiu retrospectiv.

UNLABELLED: Lipomas are the most common soft tissue mesenchymal neoplasms, with 15 to 20% of the cases involving the head and neck region and 1 to 4% affecting the oral cavity. They represent 0.1 to 5% of all benign tumours of the mouth and are usually found as long-standing soft nodular asymptomatic swellings covered by normal mucosa. Few large series of intraoral lipomas and its variants are seen in literature. AIM: This study aimed to assess the clinical and histological features of intraoral lipomas. MATERIALS AND METHODS: A retrospective review was undertaken of medical records and histological studies of 19 patients with histopathologically proven intraoral lipomas, over a 15-year period (from 1992 to 2006) at the Department of Oral and Maxillofacial Surgery, Iasi. RESULTS: Most of the cases affected adults (18 cases) without gender predilection and the main involved sites were: the floor of the mouth (6 cases), the buccal mucosa (5 cases), the lips (4 cases), the tongue (3 cases) and the buccal sulcus (1 case). The histological analysis revealed 14 cases of common lipomas (3 with infiltrating features), 4 cases of fibrolipomas, and 1 myxoid lipoma. All lesions were surgically removed and none showed recurrence, regardless of the various histological subtypes. CONCLUSIONS: Lipomas should be considered in the differential diagnosis of soft-tissue head and neck masses. Even though several histological types are described, the clinical course and the surgical treatment are similar. Our study confirms the rare incidence of the oral lipomas development. Key words:

[A review of 15 years of experience in using the musculo-mucosal lingual flap]. / 15 ani de experienta in utilizarea lamboului musculo-mucozal lingual.

MATERIAL AND METHOD: In the past 15 years (1991-2005) we used the muscular-mucosal lingual flap with posterior pedicle for 82 patients. RESULTS: The main indication has been the reconstruction of the residual defects after resection of the mucosal mouth floor carcinomas (especially those located in the anterior third of the mouth or with gingival and alveolar invasion) or after resection of the gingival-alveolar mandible carcinomas with invasion of the mouth floor. Deglutition and phonation have been fully recovered at 14 to 20 days post-surgery, with temporary alterations during radiotherapy, due to radiation-induced mucositis. Mobility of the remaining of the tongue was acceptable and physiotherapy had a significant impact in recovering an intelligible phonation and for better mastication and deglutition due to compensatory hypertrophy of the lingual musculature. CONCLUSION: The muscular-mucosal lingual flap remains a good technical alternative for surgical reconstruction especially for advanced-age patients, heavy smokers or alcohol-consumers, patients with prior radiation therapy or patients with precarious co-operation for more advanced reconstructive techniques.

[CT exam and 2D and 3D reconstructions in facial tumors diagnosis]. / Aportul examenului CT si al reconstructiilor 2D si 3D in diagnosticul tumorilor masivului facial.

UNLABELLED: This study presents the CT imaging of a group of maxillofacial tumors that include benign tumors and primary and secondary malignant processes. MATERIAL AND METHOD: All patients were CT explored with and without intravenous contrast, using specific head and neck protocols. RESULTS: We studied the topography of the tumors, their impact on neighborhood regions and post-treatment results. The diagnostic of all patients had histological confirmation. In maxillofacial tumors and tumor-like diseases, 3D imaging was significantly superior to 2D axial imaging in showing the tumor shape and spatial relationships between tumors and surrounding structures. Two dimensional imaging and MPR imaging were excellent to reveal internal structure and pathological changes of tumors. 2D imaging and MPR imaging also achieved better results in showing tumors extended to soft tissues.

[The utilization of Dacron as interposition material in the treatment of the temporomandibular ankylosis--retrospective study: 1993-2005]. / Utilizarea dacronului ca material de interpozitie în tratamentul anchilozei temporomandibulare studiu retrospectiv 1993-2005.

The treatment of temporomandibular ankylosis, indifferently by anatomoclinical type or etiologic factor (trauma, infection, rheumatism), is exclusively surgical. The frequent indication in the temporomandibular ankylosis of types I and II Topazian remains the neo-articular modeling osteotomy with or without interposition. A clinical and retrospective study of 25 patients diagnosed with temporomandibular ankylosis (unilateral or bilateral) was performed. The patients were operated between 1993- 2005 by interpositional arthroplasty after resection of the joint osseous block. From 32 surgical procedures in temporomandibular ankylosis, the Dacron was used for 29 interventions. The qualities of this material were confirmed by good results obtained after 1-12 years of following. The mobility of the mandible and postoperative mouth opening were in normal limits with lack of complications or recurrences. The technique is simple and the interposition material is well tolerated by the body. The Dacron texture is soft, elastic, resistant with physically and chemically stable. It is easy to be modeled, perfectly adaptable on resting osseous mass, and it is integrates intra new joint by penetration of the connective fibrous in itself. Given these facts, the interposition material of Dacron plays the role of the fibrocartilage in the temporomandibular joint.

[The value of radical surgical treatment in benign symmetric lipomatosis]. / Importanta tratamentului chirurgical radical în lipomatoza simetrica benigna.

Benign symmetric lipomatosis (BSL) is a rare proliferative disorder of the adipose tissue, characterized by symmetrical fat deposits, predominantly in the neck and shoulder area, upper back and arms. This study contains the analyse of a lot of ten patients with BSL, which were surgical treated in our department between 1994-2004. The followed parameters were: sex, age, heredo-collateral antecedents, associated organic diseases, the motivation of medical addressability, the sites of first lesions, the length of evolution before the admission, methods for diagnosis, number of surgical sessions necessary to extirpation of fat deposits, the results of the periodic follow-up examination. The followed patients with BSL were treated by surgery (extirpation of the cervical fat masses): one surgical session (8 cases) or two sessions (2 cases). The morphological, functional and psychic results were good. Recurrence at the site of surgery was not detected in any follow-up subjects. The elective treatment in BSL is surgical, by extirpation of the lipomatous masses; a satisfactory, lasting result can be expected only after the most radical possible extirpation (not only for cosmetic intentions).