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1.
Phys Chem Chem Phys ; 17(33): 21709-15, 2015 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-26234563

RESUMO

An investigation of surface cleaning using a swarm of gas bubbles within an acoustically activated stream is presented. Electrolysis of water at Pt microwires (100 µm diameter) to produce both hydrogen and oxygen bubbles is shown to enhance the extent of ultrasonic surface cleaning in a free flowing water stream containing an electrolyte (0.1 M Na2SO4) and low surfactant concentration (2 mM SDS). The surfactant was employed to allow control of the average size of the bubble population within the swarm. The electrochemical bubble swarm (EBS) is shown to perturb acoustic transmission through the stream. To optimise the cleaning process both the ultrasonic field and the electrochemical current are pulsed and synchronized but with different duty cycles. Cleaning action is demonstrated on structured surfaces (porcine skin and finger mimics) loaded with fluorescent particles. This action is shown to be significantly enhanced compared to that found with an inherent bubble population produced by the flow and acoustic regime alone under the same conditions.

2.
Phys Chem Chem Phys ; 17(32): 20574-9, 2015 Aug 28.
Artigo em Inglês | MEDLINE | ID: mdl-26200694

RESUMO

In the absence of sufficient cleaning of medical instruments, contamination and infection can result in serious consequences for the health sector and remains a significant unmet challenge. In this paper we describe a novel cleaning system reliant on cavitation action created in a free flowing fluid stream where ultrasonic transmission to a surface, through the stream, is achieved using careful design and control of the device architecture, sound field and the materials employed. Cleaning was achieved with purified water at room temperature, moderate fluid flow rates and without the need for chemical additives or the high power consumption associated with conventional strategies. This study illustrates the potential in harnessing an ultrasonically activated stream to remove biological contamination including brain tissue from surgical stainless steel substrates, S. epidermidis biofilms from glass, and fat/soft tissue matter from bone structures with considerable basic and clinical applications.


Assuntos
Biofilmes , Encéfalo/metabolismo , Proteínas/metabolismo , Staphylococcus epidermidis/metabolismo , Ultrassom , Água/metabolismo , Animais , Camundongos , Camundongos Endogâmicos C57BL , Proteínas/química , Aço Inoxidável/química , Temperatura , Água/química
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