Pesquisa | BVS Educação Profissional em Saúde

1.

Clinical trial links oncolytic immunoactivation to survival in glioblastoma.

Ling, Alexander L; Solomon, Isaac H; Landivar, Ana Montalvo; Nakashima, Hiroshi; Woods, Jared K; Santos, Andres; Masud, Nafisa; Fell, Geoffrey; Mo, Xiaokui; Yilmaz, Ayse S; Grant, James; Zhang, Abigail; Bernstock, Joshua D; Torio, Erickson; Ito, Hirotaka; Liu, Junfeng; Shono, Naoyuki; Nowicki, Michal O; Triggs, Daniel; Halloran, Patrick; Piranlioglu, Raziye; Soni, Himanshu; Stopa, Brittany; Bi, Wenya Linda; Peruzzi, Pierpaolo; Chen, Ethan; Malinowski, Seth W; Prabhu, Michael C; Zeng, Yu; Carlisle, Anne; Rodig, Scott J; Wen, Patrick Y; Lee, Eudocia Quant; Nayak, Lakshmi; Chukwueke, Ugonma; Gonzalez Castro, L Nicolas; Dumont, Sydney D; Batchelor, Tracy; Kittelberger, Kara; Tikhonova, Ekaterina; Miheecheva, Natalia; Tabakov, Dmitry; Shin, Nara; Gorbacheva, Alisa; Shumskiy, Artemy; Frenkel, Felix; Aguilar-Cordova, Estuardo; Aguilar, Laura K; Krisky, David; Wechuck, James.

Nature ; 623(7985): 157-166, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37853118

2.

Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma.

Mellinghoff, Ingo K; van den Bent, Martin J; Blumenthal, Deborah T; Touat, Mehdi; Peters, Katherine B; Clarke, Jennifer; Mendez, Joe; Yust-Katz, Shlomit; Welsh, Liam; Mason, Warren P; Ducray, François; Umemura, Yoshie; Nabors, Burt; Holdhoff, Matthias; Hottinger, Andreas F; Arakawa, Yoshiki; Sepulveda, Juan M; Wick, Wolfgang; Soffietti, Riccardo; Perry, James R; Giglio, Pierre; de la Fuente, Macarena; Maher, Elizabeth A; Schoenfeld, Steven; Zhao, Dan; Pandya, Shuchi S; Steelman, Lori; Hassan, Islam; Wen, Patrick Y; Cloughesy, Timothy F.

N Engl J Med ; 389(7): 589-601, 2023 Aug 17.

Artigo em Inglês | MEDLINE | ID: mdl-37272516

3.

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.

Keskin, Derin B; Anandappa, Annabelle J; Sun, Jing; Tirosh, Itay; Mathewson, Nathan D; Li, Shuqiang; Oliveira, Giacomo; Giobbie-Hurder, Anita; Felt, Kristen; Gjini, Evisa; Shukla, Sachet A; Hu, Zhuting; Li, Letitia; Le, Phuong M; Allesøe, Rosa L; Richman, Alyssa R; Kowalczyk, Monika S; Abdelrahman, Sara; Geduldig, Jack E; Charbonneau, Sarah; Pelton, Kristine; Iorgulescu, J Bryan; Elagina, Liudmila; Zhang, Wandi; Olive, Oriol; McCluskey, Christine; Olsen, Lars R; Stevens, Jonathan; Lane, William J; Salazar, Andres M; Daley, Heather; Wen, Patrick Y; Chiocca, E Antonio; Harden, Maegan; Lennon, Niall J; Gabriel, Stacey; Getz, Gad; Lander, Eric S; Regev, Aviv; Ritz, Jerome; Neuberg, Donna; Rodig, Scott J; Ligon, Keith L; Suvà, Mario L; Wucherpfennig, Kai W; Hacohen, Nir; Fritsch, Edward F; Livak, Kenneth J; Ott, Patrick A; Wu, Catherine J.

Nature ; 565(7738): 234-239, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30568305

4.

PET-based response assessment criteria for diffuse gliomas (PET RANO 1.0): a report of the RANO group.

Albert, Nathalie L; Galldiks, Norbert; Ellingson, Benjamin M; van den Bent, Martin J; Chang, Susan M; Cicone, Francesco; de Groot, John; Koh, Eng-Siew; Law, Ian; Le Rhun, Emilie; Mair, Maximilian J; Minniti, Giuseppe; Rudà, Roberta; Scott, Andrew M; Short, Susan C; Smits, Marion; Suchorska, Bogdana; Tolboom, Nelleke; Traub-Weidinger, Tatjana; Tonn, Joerg-Christian; Verger, Antoine; Weller, Michael; Wen, Patrick Y; Preusser, Matthias.

Lancet Oncol ; 25(1): e29-e41, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38181810

5.

Joint EANM/EANO/RANO/SNMMI practice guideline/procedure standards for diagnostics and therapy (theranostics) of meningiomas using radiolabeled somatostatin receptor ligands: version 1.0.

Albert, Nathalie L; Preusser, Matthias; Traub-Weidinger, Tatjana; Tolboom, Nelleke; Law, Ian; Palmer, Joshua D; Guedj, Eric; Furtner, Julia; Fraioli, Francesco; Huang, Raymond Y; Johnson, Derek R; Deroose, Christophe M; Herrmann, Ken; Vogelbaum, Michael; Chang, Susan; Tonn, Joerg-Christian; Weller, Michael; Wen, Patrick Y; van den Bent, Martin J; Verger, Antoine; Ivanidze, Jana; Galldiks, Norbert.

Eur J Nucl Med Mol Imaging ; 2024 Jun 20.

Artigo em Inglês | MEDLINE | ID: mdl-38898354

6.

Updated Response Assessment in Neuro-Oncology (RANO) for Gliomas.

Youssef, Gilbert; Wen, Patrick Y.

Curr Neurol Neurosci Rep ; 24(2): 17-25, 2024 02.

Artigo em Inglês | MEDLINE | ID: mdl-38170429

7.

Current drug development and trial designs in neuro-oncology: report from the first American Society of Clinical Oncology and Society for Neuro-Oncology Clinical Trials Conference.

Rahman, Rifaquat; Polley, Mei-Yin C; Alder, Laura; Brastianos, Priscilla K; Anders, Carey K; Tawbi, Hussein A; Mehta, Minesh; Wen, Patrick Y; Geyer, Susan; de Groot, John; Zadeh, Gelareh; Piantadosi, Steven; Galanis, Evanthia; Khasraw, Mustafa.

Lancet Oncol ; 24(4): e161-e171, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36990614

8.

Novel trial designs in neuro-oncology.

Song, Kun-Wei; Wen, Patrick Y.

Curr Opin Neurol ; 36(6): 571-578, 2023 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-37865854

9.

Activity of a first-in-class oral HIF2-alpha inhibitor, PT2385, in patients with first recurrence of glioblastoma.

Strowd, Roy; Ellingson, Benjamin; Raymond, Catalina; Yao, Jingwen; Wen, Patrick Y; Ahluwalia, Manmeet; Piotrowski, Anna; Desai, Arati; Clarke, Jennifer L; Lieberman, Frank S; Desideri, Serena; Nabors, L Burt; Ye, Xiaobu; Grossman, Stuart.

J Neurooncol ; 165(1): 101-112, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37864646

10.

Molecular Profiling and Targeted Therapies in Gliomas.

Felistia, Yuli; Wen, Patrick Y.

Curr Neurol Neurosci Rep ; 23(10): 627-636, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37812369

11.

Therapeutic avenues for cancer neuroscience: translational frontiers and clinical opportunities.

Shi, Diana D; Guo, Jimmy A; Hoffman, Hannah I; Su, Jennifer; Mino-Kenudson, Mari; Barth, Jaimie L; Schenkel, Jason M; Loeffler, Jay S; Shih, Helen A; Hong, Theodore S; Wo, Jennifer Y; Aguirre, Andrew J; Jacks, Tyler; Zheng, Lei; Wen, Patrick Y; Wang, Timothy C; Hwang, William L.

Lancet Oncol ; 23(2): e62-e74, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-35114133

12.

Dabrafenib plus trametinib in patients with BRAF^V600E-mutant low-grade and high-grade glioma (ROAR): a multicentre, open-label, single-arm, phase 2, basket trial.

Wen, Patrick Y; Stein, Alexander; van den Bent, Martin; De Greve, Jacques; Wick, Antje; de Vos, Filip Y F L; von Bubnoff, Nikolas; van Linde, Myra E; Lai, Albert; Prager, Gerald W; Campone, Mario; Fasolo, Angelica; Lopez-Martin, Jose A; Kim, Tae Min; Mason, Warren P; Hofheinz, Ralf-Dieter; Blay, Jean-Yves; Cho, Daniel C; Gazzah, Anas; Pouessel, Damien; Yachnin, Jeffrey; Boran, Aislyn; Burgess, Paul; Ilankumaran, Palanichamy; Gasal, Eduard; Subbiah, Vivek.

Lancet Oncol ; 23(1): 53-64, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34838156

13.

Survival outcomes associated with MGMT promoter methylation and temozolomide in gliosarcoma patients.

Kavouridis, Vasileios K; Ligon, Keith L; Wen, Patrick Y; Iorgulescu, J Bryan.

J Neurooncol ; 158(1): 111-116, 2022 May.

Artigo em Inglês | MEDLINE | ID: mdl-35474499

14.

DICER1 mutations in primary central nervous system tumors: new insights into histologies, mutations, and prognosis.

Liu, Kevin X; Shang, Helen H; Cacciotti, Chantel; Everdell, Emily; Aizer, Ayal A; Rahman, Rifaquat; Malinowski, Seth; Meredith, David M; Kamihara, Junne; Wen, Patrick Y; Ligon, Keith L; Chi, Susan N; Marcus, Karen J; Yeo, Kee Kiat; Alexandrescu, Sanda; Haas-Kogan, Daphne A.

J Neurooncol ; 157(3): 499-510, 2022 May.

Artigo em Inglês | MEDLINE | ID: mdl-35384518

15.

Leveraging external data in the design and analysis of clinical trials in neuro-oncology.

Rahman, Rifaquat; Ventz, Steffen; McDunn, Jon; Louv, Bill; Reyes-Rivera, Irmarie; Polley, Mei-Yin C; Merchant, Fahar; Abrey, Lauren E; Allen, Joshua E; Aguilar, Laura K; Aguilar-Cordova, Estuardo; Arons, David; Tanner, Kirk; Bagley, Stephen; Khasraw, Mustafa; Cloughesy, Timothy; Wen, Patrick Y; Alexander, Brian M; Trippa, Lorenzo.

Lancet Oncol ; 22(10): e456-e465, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34592195

16.

IDH-mutant gliomas with additional class-defining molecular events.

Ahrendsen, Jared T; Torre, Matthew; Meredith, David M; Hornick, Jason L; Reardon, David A; Wen, Patrick Y; Yeo, Kee K; Malinowski, Seth; Ligon, Keith L; Ramkissoon, Shakti; Alexandrescu, Sanda.

Mod Pathol ; 34(7): 1236-1244, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-33772213

17.

Clinical, radiological and genomic features and targeted therapy in BRAF V600E mutant adult glioblastoma.

Lim-Fat, Mary Jane; Song, Kun Wei; Iorgulescu, J Bryan; Andersen, Brian M; Forst, Deborah A; Jordan, Justin T; Gerstner, Elizabeth R; Reardon, David A; Wen, Patrick Y; Arrillaga-Romany, Isabel.

J Neurooncol ; 152(3): 515-522, 2021 May.

Artigo em Inglês | MEDLINE | ID: mdl-33646525

18.

Medical and Neurological Management of Brain Tumor Complications.

Youssef, Gilbert; Wen, Patrick Y.

Curr Neurol Neurosci Rep ; 21(10): 53, 2021 09 20.

Artigo em Inglês | MEDLINE | ID: mdl-34545509

19.

Dabrafenib plus trametinib in patients with BRAF^V600E-mutated biliary tract cancer (ROAR): a phase 2, open-label, single-arm, multicentre basket trial.

Subbiah, Vivek; Lassen, Ulrik; Élez, Elena; Italiano, Antoine; Curigliano, Giuseppe; Javle, Milind; de Braud, Filippo; Prager, Gerald W; Greil, Richard; Stein, Alexander; Fasolo, Angelica; Schellens, Jan H M; Wen, Patrick Y; Viele, Kert; Boran, Aislyn D; Gasal, Eduard; Burgess, Paul; Ilankumaran, Palanichamy; Wainberg, Zev A.

Lancet Oncol ; 21(9): 1234-1243, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32818466

20.

Response assessment in paediatric high-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.

Erker, Craig; Tamrazi, Benita; Poussaint, Tina Y; Mueller, Sabine; Mata-Mbemba, Daddy; Franceschi, Enrico; Brandes, Alba A; Rao, Arvind; Haworth, Kellie B; Wen, Patrick Y; Goldman, Stewart; Vezina, Gilbert; MacDonald, Tobey J; Dunkel, Ira J; Morgan, Paul S; Jaspan, Tim; Prados, Michael D; Warren, Katherine E.

Lancet Oncol ; 21(6): e317-e329, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32502458

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