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1.
J Med Internet Res ; 23(6): e25946, 2021 06 21.
Artigo em Inglês | MEDLINE | ID: mdl-34152279

RESUMO

BACKGROUND: Recently, the problem of traditional Chinese medicine (TCM) safety has attracted attention worldwide. To prevent the spread of counterfeit drugs, it is necessary to establish a drug traceability system. A traditional drug traceability system can record the whole circulation process of drugs, from planting, production, processing, and warehousing to use by hospitals and patients. Once counterfeit drugs are found, they can be traced back to the source. However, traditional drug traceability systems have some drawbacks, such as failure to prevent tampering and facilitation of sensitive disclosure. Blockchain (including Bitcoin and Ethernet Square) is an effective technology to address the problems of traditional drug traceability systems. However, some risks impact the reliability of blockchain, such as information explosion, sensitive information leakage, and poor scalability. OBJECTIVE: To avoid the risks associated with the application of blockchain, we propose a lightweight block chain framework. METHODS: In this framework, both horizontal and vertical segmentations are performed when designing the blocks, and effective strategies are provided for both segmentations. For horizontal segmentation operations, the header and body of the blockchain are separated and stored in the blockchain, and the body is stored in the InterPlanetary File System. For vertical segmentation operations, the blockchain is cut off according to time or size. For the addition of new blocks, miners only need to copy the latest part of the blockchain and append the tail and vertical segmentation of the block through the consensus mechanism. RESULTS: Our framework could greatly reduce the size of the blockchain and improve the verification efficiency. CONCLUSIONS: Experimental results have shown that the efficiency improves compared with ethernet when a new block is added to the blockchain and a search is conducted.


Assuntos
Blockchain , Hospitais , Humanos , Medicina Tradicional Chinesa , Reprodutibilidade dos Testes , Tecnologia
2.
Opt Express ; 27(21): 30852-30863, 2019 Oct 14.
Artigo em Inglês | MEDLINE | ID: mdl-31684328

RESUMO

Tamm plasmons (TPs), whose plasmon modes are confined at the Bragg reflector/metal interface due to the photonic stopband of the reflector and the negative dielectric constant of the metal, exhibit many advantages over the conventional surface plasmons (SPs) and potential applications in sensors, filters, optical circuits and light-emitting devices. In this paper, a TP-cavity structure has been proposed for accelerating the light emission and alleviating the large metal loss, which is hopeful for solving the efficiency droop and "green gap" problems in InGaN green light-emitting diodes (LEDs). The light emission performance of TP-cavity LEDs was systematically investigated based on transfer matrix and finite-difference time domain methods. Purcell factor (Fp) and light extraction efficiency (LEE) were both remarkably enhanced, which would be attributed to the presence of the TP and/or SP modes induced by the TP-cavity structure. In addition, two important factors including the thicknesses of the top Ag film and medium layer were investigated in detail and taken into account for the balance between the Fp and the LEE. Finally, light emission intensity was significantly enhanced for the TP-cavity green LEDs after the structure optimization as compared to the conventional green LEDs.

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