Is social support beneficial for military cadets to accomplish empowerment? Findings from a long-term cross-lagged panel analysis.

Social support and empowerment are central to health and wellbeing. Besides, social support is often the primary means to help students improve their mental health and accomplish empowerment. However, military academies are an atypical form of tertiary education. Is social support still beneficial for military cadets to accomplish empowerment? Or does empowerment influence the extent of social support a person receives? This study sought to examine the reciprocal relationships between social support and empowerment in military academies, as well as to examine the sex differences in this model. A longitudinal panel survey of military cadets was carried out from the years 2019 to 2021. A crosslagged path model design was used on a sample of military cadets (N = 898) measured on three occasions one year apart. The results suggested that no cross-lagged associations between social support and empowerment. The three-year panel data consistently showed that social support does not enhance military cadets' empowerment, whereas empowerment significantly influences their perceived social support. Furthermore, there were no sex differences in this model. Finally, the findings informed practitioners and future research could be pay attention to the particularity in military settings, in order to provide adequate interventions and services for military cadets.

Vascular endothelial growth factor -634G/C and vascular endothelial growth factor -2578C/A polymorphisms and lung cancer risk: a case-control study and meta-analysis.

Vascular endothelial growth factor (VEGF) is a major regulator of angiogenesis in the process of tumor growth and metastasis. In present study, we conducted a case-control study and meta-analysis to evaluate the genetic effects of VEGF -634G/C and VEGF -2578C/A polymorphisms and risk of lung cancer. A total of 175 subjects were recruited for case-control study and seven studies were included in the meta-analysis. Our case-control study showed that VEGF -634G/C polymorphism had no association with lung cancer risk (CC vs. GG: OR = 0.88, 95% CI = 0.37-2.11), whereas there was an association between VEGF -2578CC genotype and decrease in lung cancer risk (CC vs. CA/AA: OR = 0.52, 95% CI = 0.28-0.96). A meta-analysis was further performed and statistically similar results were obtained (CC vs. GG: OR = 0.91, 95% CI = 0.60-1.39 for VEGF -634; CC vs. AA: OR = 0.53, 95% CI = 0.32-0.89 for VEGF -2578). Our study showed that the variant genotypes of the VEGF -2578C/A polymorphism, but not the VEGF -634G/C polymorphism, was associated with lung cancer risk. More studies are needed to detect VEGF -634G/C and VEGF -2578 polymorphisms and their association with lung cancer in different ethnic populations incorporated with environmental exposures.

Macrolide therapy in cryptogenic organizing pneumonia: A case report and literature review.

Cryptogenic organizing pneumonia (COP) is a pulmonary disorder associated with nonspecific clinical presentations. The macrolide class of antimicrobial agents is widely used to treat infectious and inflammatory respiratory diseases in humans. The present study reports a case of COP that was effectively treated with azithromycin in combination with glucocorticoid. A literature review of similar cases is also presented. It was found that all COP patients in the literature received macrolide treatment, including six cases with unknown clinical outcomes. For the remaining 29 patients, 20 patients initially received the macrolide as a single therapy and 4/5 of them (16 cases) were cured with a treatment time of 3-14 months, while 1/5 (4 cases) showed no improvement after treatment for 1 month and were switched to a glucocorticoid or combination treatment with a glucocorticoid, after which the disease was finally well-controlled. Side-effects of macrolide were rare. Based on this analysis, it is recommended that macrolides can be used as a first-line therapy in patients with mild COP. For patients with recurrent COP, it is suggested that macrolides should be used as an adjunctive therapy with other treatments, such as a glucocorticoid.

Three new species of the Stenuscirrus group (Coleoptera, Staphylinidae) from Jiangxi, South China.

THREE NEW SPECIES FROM JIANGXI, CHINA, ARE DESCRIBED AND ILLUSTRATED: Stenuswugongshanus sp. n., Stenusmingyueshanus sp. n., and Stenussongxiaobini sp. n. A previously published key to the Chinese species of the Stenuscirrus group is modified to accommodate the new species.

Evaluation of VEGF-C and tumor markers in bronchoalveolar lavage fluid for lung cancer diagnosis.

A total of 87 patients were enrolled and bronchoalveolar lavage fluid (BALF) samples were obtained from all subjects. A significant difference was found in BALF VEGF-C level between patients with squamous cell carcinoma and benign diseases (P = 0.043). In addition, the concentration of NSE in BALF form the malignant group was significantly higher compared with that of the benign groups (P = 0.018). However, no statistical difference was observed in BALF CEA (P = 0.375) or CYFRA21-1 (P = 0.838) between lung cancer patients and nonmalignant controls. With a cut-off value of 2.06 ng/ml, NSE had a sensitivity of 72.9%, a specificity of 69.2%, respectively, in predicting the malignant nature of pulmonary mass. Our study observed that the level of VEGF-C was increased in BALF of patients with squamous cell carcinoma. Moreover, we found that NSE was significantly higher in BALF of lung cancer patients than in benign diseases.

Polymorphism of vascular endothelial growth factor -2578C/A with cancer risk: evidence from 11263 subjects.

Published data on the association between vascular endothelial growth factor (VEGF) -2578C/A polymorphism and cancer risk is inconclusive. To derive a more precise estimation of association between VEGF -2578C/A polymorphism and the risk of cancer, we performed a meta-analysis of 5415 cancer cases and 5848 controls from 16 published case-control studies. We used odds ratios (ORs) with 95% confidence intervals (CIs) to assess the strength of the association. Our meta-analysis indicated that VEGF -2578C/A polymorphism was associated with the risk of colorectal cancer under homozygote comparison (OR=0.70, 95% CI=0.53-0.92), dominant model (OR=0.72, 95% CI=0.57-0.92), and recessive model (OR=0.82, 95% CI=0.67-1.01), although no evidence of association between VEGF -2578C/A polymorphism and cancer risk was observed as we compared in the pooled analyses (homozygote comparison: OR=0.97, 95% CI=0.81-1.16). More studies are needed to detect VEGF -2578C/A polymorphism and its association with cancer in different ethnic populations incorporated with environmental exposures in the susceptibility of different kinds of cancer.

Excision repair cross complementation group 1 polymorphisms and lung cancer risk: a meta-analysis.

BACKGROUND: Several studies have evaluated the association between polymorphisms of encoding excision repair cross complementation group 1 (ERCC1) enzyme and lung cancer risk in diverse populations but with conflicting results. By pooling the relatively small samples in each study, it is possible to perform a meta-analysis of the evidence by rigorous methods. METHODS: Embase, Ovid, Medline and Chinese National Knowledge Infrastructure were searched. Additional studies were identified from references in original studies or review articles. Articles meeting the inclusion criteria were reviewed systematically, and the reported data were aggregated using the statistical techniques of meta-analysis. RESULTS: We found 3810 cases with lung cancer and 4332 controls from seven eligible studies. T19007C polymorphism showed no significant effect on lung cancer risk (C allele vs. T allele: odds ratio (OR) = 0.91, 95% confidence interval (CI) = 0.80 - 1.04; CC vs. TT: OR = 0.76, 95%CI = 0.56 - 1.02; CC vs. (CT + TT): OR = 0.96, 95%CI = 0.84 - 1.10). Similarly, there was no significant main effects for T19007C polymorphism on lung cancer risk when stratified analyses by ethnicity (Chinese or Caucasian). No significant association was found between C8092A polymorphism (3060 patients and 2729 controls) and the risk of lung cancer (A allele vs. C allele: OR = 1.03, 95%CI = 0.95 - 1.11; AA vs. CC: OR = 1.08, 95%CI = 0.88 - 1.33; AA vs. (AC + CC): OR = 1.08, 95%CI = 0.88 - 1.31). CONCLUSION: We found little evidence of an association between the T1900C or C8092A polymorphisms of ERCC 1 and the risk of lung cancer in Caucasian or Han Chinese people.

Vascular endothelial growth factor +936C/T and +405G/C polymorphisms and cancer risk: a meta-analysis.

BACKGROUND AND AIMS: A number of investigators have studied the possible association between vascular endothelial growth factor (VEGF) polymorphisms and cancer risk, but the results have been conflicting. To examine the risk of cancer associated with the +936C/T and +405G/C polymorphisms of VEGF, all available studies were considered in the present meta-analysis. METHODS: We performed a computerized search of PubMed and Embase database for relevant studies. Articles meeting the inclusion criteria were reviewed systematically, and the reported data were aggregated using the statistical techniques of meta-analysis. RESULTS: Overall, the 936C allele showed no significant effect on cancer risk compared with the 936T allele in all subjects (OR = 0.77, 95% CI = 0.53-1.14; random model). Similarly, no significant effect of 405G allele compared with 405C on cancer risk was found (OR = 1.08, 95% CI = 0.94-1.24; random model). It indicated that the VEGF +936C/T and +405G/C polymorphisms might not be risk factors for cancer, but the 936C allele was associated with a decreased risk of oral cancer (OR = 0.72, 95% CI = 0.53-0.97; fixed model). CONCLUSIONS: The evidence from our meta-analysis supports that there was an association between 936C allele and decreased oral cancer risk, although no evidence of association between VEGF +936C/T or +405G/C polymorphism and cancer was observed in all examined patients. Further studies based on larger, stratified population are required to explore the role of VEGF polymorphisms on cancer risk.

[Clinical analysis of colour distribution in tetracycline teeth].

PURPOSE: To analyze the colour range and distribution of tetracycline teeth, and the difference from normal teeth. METHODS: 142 cases with 468 anterior tetracycline teeth and 100 cases with 200 normal anterior teeth were collected. The color was measured by a computer-aided Shade-Eye NCC colorimeter, and expressed in terms of 3 coordinate values (L,a,b) of the CIE-1976-Lab color system. Chroma (Cab)and hue (h(ab) degrees)were calculated according to the value of a and b. The data were analyzed with SAS6.12 software package for description, Student's t test and Duncan test. RESULTS: The range of L, a, b Cab, h(ab) degrees of tetracycline teeth was 42.33-77.00, -0.6-9.6, 2.67-31.5, 5.24-31.89, 38.62 degrees-95.47 degrees, respectively. Significant difference of L value and hue (h(ab) degrees) was found between tetracycline teeth and normal teeth (P < 0.01), which indicated that tetracycline teeth were darker and redder than normal teeth. There was no difference of chroma (Cab) between tetracycline teeth and normal teeth (P > 0.05). Moreover there was significant difference of L value between canine and central incisor, and of H value (h(ab) degrees) between canine and lateral incisor in tetracycline teeth, which indicated that canine was darker and redder than incisor, and redder than lateral incisor, but there was no significant difference in chroma (Cab) among all anterior teeth and no difference in L, a, b between central incisor and lateral incisor. CONCLUSIONS: The study showed the color distribution of tetracycline teeth was wider and more dispersive than normal teeth, and much darker and redder than normal teeth. Supported by Shanghai Leading Academic Discipline

[Treatment of advanced periodontal and periapical lesion caused by malformed lingual groove with guided tissue regeneration: report of one case].

This paper reported one case with severe periodontal lesions caused by malformed lingual groove treated by guided tissue regeneration. The periodontal lesion was exposed palatally after the tooth had been treated with root canal therapy, the alveolar bone and the root surface was prepared, an unabsorbable member of e-PTFE was placed into the wound,and removed after 4 weeks, the patient was followed up for 3 years. The lesion recovered well three years after the operation, all of the periodontal tissue was in a healthy condition. It is advisable that guided periodontal tissue regeneration can be used as a new method to treat periodontal destruction induced by malformed lingual groove.