RESUMO
OBJECTIVE: This study was undertaken to identify the prognostic indicators associated with postpartum regression of cervical dysplasia diagnosed in pregnancy. STUDY DESIGN: A retrospective cohort study of pregnant women referred for colposcopy from 2004-2007 at four academic centers. RESULTS: One thousand seventy-nine patients were identified. Colposcopic impression by cervical cytology is detailed later in the text. Of patients who underwent biopsy, results correlated with or were less severe than colposcopic impression in 83% with CIN 1 and 56% with CIN 2/3. Fifty-seven percent had follow-up postpartum, with 61% reverting to normal. Resolution of cervical dysplasia was inversely associated with smoking (P = .002). No progression to cancer occurred during pregnancy. CONCLUSION: Colposcopic impression in pregnancy correlated with cervical biopsy results and postpartum colposcopic findings when performed by expert colposcopists. A high proportion of cervical dysplasia regressed postpartum. Cervical biopsies in pregnancy may not be necessary unless invasive cancer is suspected.
Assuntos
Complicações Neoplásicas na Gravidez/epidemiologia , Resultado da Gravidez , Displasia do Colo do Útero/epidemiologia , Displasia do Colo do Útero/patologia , Neoplasias Uterinas/patologia , Centros Médicos Acadêmicos , Adulto , Distribuição por Idade , Biópsia por Agulha , Estudos de Coortes , Colposcopia/métodos , Feminino , Seguimentos , Idade Gestacional , Humanos , Imuno-Histoquímica , Incidência , Análise Multivariada , Lesões Pré-Cancerosas/epidemiologia , Lesões Pré-Cancerosas/patologia , Gravidez , Complicações Neoplásicas na Gravidez/patologia , Cuidado Pré-Natal , Probabilidade , Modelos de Riscos Proporcionais , Estudos Retrospectivos , Medição de Risco , Displasia do Colo do Útero/diagnóstico , Neoplasias Uterinas/diagnóstico , Neoplasias Uterinas/epidemiologia , Esfregaço Vaginal , Adulto JovemRESUMO
BACKGROUND: Ovarian lipomas are a rare entity, with most being described as part of a teratomatous origin. This is a case report of a lipoma of an ovary not associated with a teratoma or an hyperandrogenic state. CASE: A 66-year-old female underwent an exploratory laparotomy and a left ovarian tumor measuring about 7 to 8 cm was removed. Microscopic examination demonstrated a pattern of proliferation of benign adipose tissue with focal areas of fibrovascular septae and no other tissue of different origin. CONCLUSIONS: A MEDLINE search did not reveal any well-documented cases of a pure ovarian lipoma. The cases reported were associated with teratomas, lipid cell tumors, and lipoleiomyomas. Thus, it appears that lipomas of the ovary are rare, but can occur.