RESUMO
We report on a patient in Austria with scalp eschar and neck lymphadenopathy. Rickettsial etiology was excluded by culture, PCR, and serologic tests. Borrelia afzelii was identified from the eschar swab by PCR. Lyme borreliosis can mimic rickettsiosis; appropriate tests should be included in the diagnostic workup of patients with eschars.
Assuntos
Grupo Borrelia Burgdorferi , Doença de Lyme , Infecções por Rickettsia , Áustria , Humanos , Doença de Lyme/diagnóstico , Infecções por Rickettsia/diagnóstico , Couro CabeludoRESUMO
Bacteria genetically related to Coxiella burnetii have been found in ticks. Using molecular techniques, we detected Coxiella-like bacteria, here named Candidatus Coxiella massiliensis, in skin biopsy samples and ticks removed from patients with an eschar. This organism may be a common agent of scalp eschar and neck lymphadenopathy after tick bite.
Assuntos
Coxiella/classificação , Coxiella/genética , Infecções por Bactérias Gram-Negativas/microbiologia , Infecções por Bactérias Gram-Negativas/transmissão , Carrapatos/microbiologia , Animais , Feminino , Genes Bacterianos , Humanos , Masculino , Filogenia , Doenças Transmitidas por Carrapatos/microbiologia , Doenças Transmitidas por Carrapatos/transmissãoRESUMO
Fifteen years after the initial detection of Rickettsia slovaca in ticks in Portugal, 3 autochthonous cases of R. slovaca infection were diagnosed in humans. All patients had an eschar on the scalp and lymphadenopathy; 2 patients had facial edema. R. slovaca infection was confirmed by serologic testing, culture, and PCR.
Assuntos
Infecções por Rickettsia/diagnóstico , Rickettsia/imunologia , Doenças Transmitidas por Carrapatos/diagnóstico , Adulto , Animais , Chlorocebus aethiops , Feminino , Humanos , Pessoa de Meia-Idade , Portugal , Rickettsia/isolamento & purificação , Infecções por Rickettsia/imunologia , Infecções por Rickettsia/transmissão , Couro Cabeludo/patologia , Doenças Transmitidas por Carrapatos/imunologia , Doenças Transmitidas por Carrapatos/transmissão , Células VeroRESUMO
SENLAT syndrome, also known as TIBOLA/DEBONEL, is an emerging disease in France. The major symptoms are necrotic eschar on the scalp associated with painful cervical lymphadenopathy. It occurs mainly in women and children during the cold seasons after a bite by a Dermacentor tick, responsible for transmitting Rickettsia slovaca or Rickettsia raoultii. Cutaneous swabs are safe, easy and reliable tools that should be used routinely by physicians to confirm diagnosis. In this particular disease, they should be preferred to serology, which is less sensitive. Doxycycline is the antibiotic of choice for this syndrome.