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1.
Neuroimage ; 299: 120796, 2024 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-39153523

RESUMO

PURPOSE: In this study, the objectification of the subjective perception of loudness was investigated using electroencephalography (EEG). In particular, the emergence of objective markers in the domain of the acoustic discomfort threshold was examined. METHODS: A cohort of 27 adults with normal hearing, aged between 18 and 30, participated in the study. The participants were presented with 500 ms long noise stimuli via in-ear headphones. The acoustic signals were presented with sound levels of [55, 65, 75, 85, 95 dB]. After each stimulus, the subjects provided their subjective assessment of the perceived loudness using a colored scale on a touchscreen. EEG signals were recorded, and afterward, event-related potentials (ERPs) locked to sound onset were analyzed. RESULTS: Our findings reveal a linear dependency between the N100 component and both the sound level and the subjective loudness categorization of the sound. Additionally, the data demonstrated a nonlinear relationship between the P300 potential and the sound level as well as for the subjective loudness rating. The P300 potential was elicited exclusively when the stimuli had been subjectively rated as "very loud" or "too loud". CONCLUSION: The findings of the present study suggest the possibility of the identification of the subjective uncomfortable loudness level by objective neural parameters.


Assuntos
Eletroencefalografia , Percepção Sonora , Humanos , Adulto , Masculino , Feminino , Eletroencefalografia/métodos , Adulto Jovem , Percepção Sonora/fisiologia , Adolescente , Potenciais Evocados P300/fisiologia , Estimulação Acústica , Potenciais Evocados Auditivos/fisiologia , Encéfalo/fisiologia , Potenciais Evocados/fisiologia
2.
Cereb Cortex ; 33(16): 9542-9553, 2023 08 08.
Artigo em Inglês | MEDLINE | ID: mdl-37344250

RESUMO

Segregation and integration are two fundamental yet competing computations in cognition. For example, in serial speech processing, stable perception necessitates the sequential establishment of perceptual representations to remove irrelevant features for achieving invariance. Whereas multiple features need to combine to create a coherent percept. How to simultaneously achieve seemingly contradicted computations of segregation and integration in a serial process is unclear. To investigate their neural mechanisms, we used loudness and lexical tones as a research model and employed a novel multilevel oddball paradigm with Electroencephalogram (EEG) recordings to explore the dynamics of mismatch negativity (MMN) responses to their deviants. When two types of deviants were presented separately, distinct topographies of MMNs to loudness and tones were observed at different latencies (loudness earlier), supporting the sequential dynamics of independent representations for two features. When they changed simultaneously, the latency of responses to tones became shorter and aligned with that to loudness, while the topographies remained independent, yielding the combined MMN as a linear additive of single MMNs of loudness and tones. These results suggest that neural dynamics can be temporally synchronized to distinct sensory features and balance the computational demands of segregation and integration, grounding for invariance and feature binding in serial processing.


Assuntos
Eletroencefalografia , Percepção da Fala , Eletroencefalografia/métodos , Percepção da Fala/fisiologia , Fala , Potenciais Evocados Auditivos/fisiologia , Estimulação Acústica/métodos
3.
Perception ; 53(7): 450-464, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38778785

RESUMO

This study aimed to investigate the perception of loudness in response to changes in fundamental frequency (F0) in spoken sounds, as well as the influence of linguistic background on this perceptual process. The results revealed that participants perceived changes in F0 to have accompanying changes in loudness, with a trend of lower F0 sounds being perceived as louder than higher F0 sounds. This finding contrasts with previous studies on pure tones, where increases in frequency typically led to increases in loudness. Furthermore, the study examined differences between two distinct groups of participants: Chinese-speaking and English-speaking individuals. It was observed that English-speaking participants exhibited a greater sensitivity to minor intensity changes compared to Chinese-speaking participants. This discrepancy in sensitivity suggests that linguistic background may play a significant role in shaping the perception of loudness in spoken sound. The study's findings contribute to our understanding of how F0 variations are perceived in terms of loudness, and highlight the potential impact of language experience on this perceptual process.


Assuntos
Percepção Sonora , Percepção da Fala , Humanos , Masculino , Feminino , Percepção Sonora/fisiologia , Adulto , Adulto Jovem , Percepção da Fala/fisiologia , Acústica da Fala , Idioma
4.
Eur Arch Otorhinolaryngol ; 281(1): 61-66, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37417997

RESUMO

PURPOSE: Cochlear implants are usually activated 3-5 weeks after surgery; to date, no universal protocol exists regarding switch on and fitting of these devices. The aim of the study was to assess safety and functional results of activation and fitting of cochlear implant within 24 h following surgery. METHODS: In this retrospective case-control study, 15 adult patients who underwent cochlear implant surgery, for a total of 20 cochlear implant procedures were analyzed. In particular, clinical safety and feasibility were investigated by examinating patients at activation and at each follow-up. Values of electrodes' impedance and most comfortable loudness (MCL) were analyzed from the time of surgery to 12 months after activation. Free-field pure tone average (PTA) was also recorded. RESULTS: No major or minor complications were reported and all patients could perform the early fitting. Activation modality influenced impedance values only in the short term but the differences were not statistically significant (p > 0.05). Mean MCL values in the early fitting group were lower than MCL of the late fitting in all follow-up sessions, and the difference was statistically significant (p < 0.05). The mean PTA was lower in the early fitting group but the difference was not statistically significant (p < 0.05). CONCLUSIONS: Early fitting of cochlear implants is safe, allows for an early rehabilitation and can have possible beneficial effects on stimulation levels and dynamic range.


Assuntos
Implante Coclear , Implantes Cocleares , Adulto , Humanos , Estudos Retrospectivos , Estudos de Casos e Controles , Implante Coclear/métodos , Impedância Elétrica
5.
Int J Audiol ; : 1-6, 2024 Mar 22.
Artigo em Inglês | MEDLINE | ID: mdl-38519436

RESUMO

OBJECTIVE: To develop an improved version of the profile of aided loudness (PAL), intended for assessment of the appropriateness of the loudness of everyday sounds. DESIGN: Initially, 16 participants with a range of ages and degrees of hearing loss indicated whether they encountered each situation described in the PAL and how specific they considered the description to be. Based on the responses, most situations from the PAL were eliminated and new situations were introduced, giving the Cambridge Aided Loudness Profile (CALP). The CALP was administered to 80 young and 22 older participants with normal hearing, who rated the loudness of each situation and satisfaction with this loudness (as for the original PAL). Satisfaction was strongly negatively correlated with loudness, suggesting that satisfaction was largely based on loudness. The CALP was then administered to 32 new young normal-hearing participants and 49 older participants with hearing loss, most of whom used hearing aids, who rated loudness and the appropriateness of loudness. RESULTS: Some situations were rated as loud but appropriate in loudness, indicating that the CALP can distinguish these aspects. CONCLUSIONS: The CALP questions were understood by all participants. The CALP may be useful for assessing the appropriateness of loudness.

6.
HNO ; 72(Suppl 1): 56-62, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37812257

RESUMO

BACKGROUND: One of the main treatment goals in cochlear implant (CI) patients is to improve speech perception. One of the target parameters is speech intelligibility in quiet. However, treatment results show a high variability, which has not been sufficiently explained so far. The aim of this noninterventional retrospective study was to elucidate this variability using a selected population of patients in whom etiology was not expected to have a negative impact on postoperative speech intelligibility. MATERIALS AND METHODS: Audiometric findings of the CI follow-up of 28 adult patients after 6 months of CI experience were evaluated. These were related to the preoperative audiometric examination and evaluated with respect to a recently published predictive model for the postoperative monosyllabic score. RESULTS: Inclusion of postoperative categorical loudness scaling and hearing loss for Freiburg numbers in the model explained 55% of the variability in fitting outcomes with respect to monosyllabic word recognition. CONCLUSION: The results of this study suggest that much of the cause of variability in fitting outcomes can be captured by systematic postoperative audiometric checks. Immediate conclusions for CI system fitting adjustments may be drawn from these results. However, the extent to which these are accepted by individual patients and thus lead to an improvement in outcome must be subject of further studies, preferably prospective.


Assuntos
Implante Coclear , Implantes Cocleares , Percepção da Fala , Adulto , Humanos , Estudos Retrospectivos , Estudos Prospectivos , Implante Coclear/métodos , Audiometria
7.
J Neurosci ; 42(44): 8252-8261, 2022 11 02.
Artigo em Inglês | MEDLINE | ID: mdl-36113990

RESUMO

The identity and location of vocalization pattern generating (VPG) circuits in mammals is debated. Based on physiological experiments, investigators suggested anterior brainstem circuits in the reticular formation, and anatomic evidence suggested the nucleus retroambiguus (NRA) in the posterior brainstem, or combinations of these sites as the putative mammalian VPG. Additionally, vocalization loudness is a critical factor in acoustic communication. However, many of the underlying neuronal mechanisms are still unknown. Here, we evoked calls by stimulation of the periaqueductal gray in anesthetized male rats, performed a large-scale mapping of vocalization-related activity using the activity marker c-fos, and high-density recordings of brainstem circuits using Neuropixels probes. Both c-fos expression and recording of vocalization-related activity point to a participation of the NRA in vocalization. More important, among our recorded structures, we found that the NRA is the only brainstem area showing a strong correlation between unit activity and call intensity. In addition, we observed functionally diverse patterns of vocalization-related activity in a set of regions around NRA. Dorsal to NRA, we observed activity specific to the beginning and end of vocalizations in the posterior level of the medullary reticular nucleus, dorsal part, whereas medial and lateral to the NRA, we observed activity related to call initiation. No clear vocalization-related activity was observed at anterior brainstem sites. Our findings suggest a set of functionally heterogeneous regions around the NRA contribute to vocal pattern generation in rats.SIGNIFICANCE STATEMENT Vocalization patterns are shaped in the mammalian brainstem, but the identity and location of the circuits involved is debated. Additionally, the neuronal mechanisms of vocal intensity control are still unknown. This study consisted of a large-scale mapping of brainstem vocalization circuits based on the activity marker c-fos and high-density recordings with Neuropixels probes. The results confirm the role of nucleus retroambiguus in call production and point to a key role of neurons in this nucleus in loudness control. Dorsal to the nucleus retroambiguus and in the posterior medulla, the authors identify neurons with activity specific to the beginning and end of vocalizations. The results point to specific neural dials for various aspects of rat vocalization control in the posterior brainstem.


Assuntos
Tronco Encefálico , Vocalização Animal , Ratos , Masculino , Animais , Vocalização Animal/fisiologia , Tronco Encefálico/fisiologia , Bulbo/fisiologia , Substância Cinzenta Periaquedutal/fisiologia , Formação Reticular , Mamíferos
8.
Brain Topogr ; 36(5): 686-697, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37393418

RESUMO

BACKGROUND: Functional near-infrared spectroscopy (fNIRS) is a viable non-invasive technique for functional neuroimaging in the cochlear implant (CI) population; however, the effects of acoustic stimulus features on the fNIRS signal have not been thoroughly examined. This study examined the effect of stimulus level on fNIRS responses in adults with normal hearing or bilateral CIs. We hypothesized that fNIRS responses would correlate with both stimulus level and subjective loudness ratings, but that the correlation would be weaker with CIs due to the compression of acoustic input to electric output. METHODS: Thirteen adults with bilateral CIs and 16 with normal hearing (NH) completed the study. Signal-correlated noise, a speech-shaped noise modulated by the temporal envelope of speech stimuli, was used to determine the effect of stimulus level in an unintelligible speech-like stimulus between the range of soft to loud speech. Cortical activity in the left hemisphere was recorded. RESULTS: Results indicated a positive correlation of cortical activation in the left superior temporal gyrus with stimulus level in both NH and CI listeners with an additional correlation between cortical activity and perceived loudness for the CI group. The results are consistent with the literature and our hypothesis. CONCLUSIONS: These results support the potential of fNIRS to examine auditory stimulus level effects at a group level and the importance of controlling for stimulus level and loudness in speech recognition studies. Further research is needed to better understand cortical activation patterns for speech recognition as a function of both stimulus presentation level and perceived loudness.


Assuntos
Córtex Auditivo , Implantes Cocleares , Percepção da Fala , Adulto , Humanos , Espectroscopia de Luz Próxima ao Infravermelho/métodos , Córtex Auditivo/diagnóstico por imagem , Córtex Auditivo/fisiologia , Lobo Temporal/diagnóstico por imagem , Lobo Temporal/fisiologia , Estimulação Acústica
9.
Eur Arch Otorhinolaryngol ; 280(3): 1485-1492, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36334111

RESUMO

PURPOSE: This study aims to investigate the validity and reliability of the Khalfa's hyperacusis questionnaire (HQ) in Turkish tinnitus patients with hyperacusis using uncomfortable loudness levels (ULLs) and to determine a cutoff score for tinnitus patients specifically. MATERIALS AND METHODS: One hundred and forty subjects with a mean age ± SD of 45.27 ± 14.43 years ranging from 18 to 75 participated in the study. HQ and ULLs were used as measures of hyperacusis. The participants were divided into two groups due to ULLs ≤ 90 dB in one or both ears (Group 1) and 56 participants have ULLs > 90 dB (Group 2). RESULTS: The mean HQ score of the participants was 19.55 ± 7.18 points, Group 1 (n = 84) HQ mean score was 21.97 ± 7.08, and Group 2 (n = 56) 15.91 ± 5.56 points, and the cutoff point was found 16.50. Statistically significant differences were found between the groups in total HQ (p < 0.001), attention, social, and emotional subscales of HQ. CONCLUSIONS: Hyperacusis questionnaire using with ULLs is a precise tool for the steps of identifying, categorizing, and managing the hyperacusis in patients with tinnitus. However, the effect of the tinnitus on hyperacusis should be considered, because it causes additional problems.


Assuntos
Zumbido , Humanos , Zumbido/complicações , Zumbido/diagnóstico , Zumbido/psicologia , Hiperacusia/complicações , Hiperacusia/diagnóstico , Hiperacusia/psicologia , Reprodutibilidade dos Testes , Inquéritos e Questionários , Emoções
10.
Eur Arch Otorhinolaryngol ; 280(3): 985-1004, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36350369

RESUMO

PURPOSE: Hyperacusis is the hypersensitivity to auditory stimuli that would typically not affect those with hearing sensitivity within normal limits. The prevalence of hyperacusis in the general population has been estimated to range from 9% to 15%. There is no universally accepted definition for what defines hyperacusis among kindred illnesses of poor sound tolerance. As a result, hyperacusis prevalence varies more, which has an impact on both assessment and treatment. This study aims to determine the efficacy of the different clinical assessment measures of hyperacusis in assessing hyperacusis through a systematic review. METHODS: A review and reference of literature were done on hyperacusis, and assessment measures were used. A review of 23 articles was conducted to highlight these measures used. Most selected studies included retrospective, prospective, survey, and experimental designs. Study quality reported an overall low risk of bias. RESULTS: This review reports the summary and the current evidence of clinical assessment measures used for diagnosing hyperacusis. CONCLUSIONS: This review highlights a protocol that may be used in the clinical diagnosis of hyperacusis. It also shows the necessity to standardize and validate assessment measures for the younger population.


Assuntos
Audição , Hiperacusia , Humanos , Hiperacusia/diagnóstico , Hiperacusia/epidemiologia , Estudos Retrospectivos , Estudos Prospectivos , Testes Auditivos
11.
HNO ; 71(10): 669-677, 2023 Oct.
Artigo em Alemão | MEDLINE | ID: mdl-37450021

RESUMO

BACKGROUND: One of the main treatment goals in cochlear implant (CI) patients is to improve speech perception. One of the target parameters is speech intelligibility in quiet. However, treatment results show a high variability, which has not been sufficiently explained so far. The aim of this noninterventional retrospective study was to elucidate this variability using a selected population of patients in whom etiology was not expected to have a negative impact on postoperative speech intelligibility. MATERIALS AND METHODS: Audiometric findings of the CI follow-up of 28 adult patients after 6 months of CI experience were evaluated. These were related to the preoperative audiometric examination and evaluated with respect to a recently published predictive model for the postoperative monosyllabic score. RESULTS: Inclusion of postoperative categorical loudness scaling and hearing loss for Freiburg numbers in the model explained 55% of the variability in fitting outcomes with respect to monosyllabic comprehension. CONCLUSION: The results of this study suggest that much of the cause of variability in fitting outcomes can be captured by systematic postoperative audiometric checks. Immediate conclusions for CI system adjustments may be drawn from these results. However, the extent to which these are accepted by individual patients and thus lead to an improvement in outcome must be subject to further study, preferably prospective.


Assuntos
Implante Coclear , Implantes Cocleares , Percepção da Fala , Adulto , Humanos , Estudos Retrospectivos , Estudos Prospectivos , Implante Coclear/métodos , Audiometria , Resultado do Tratamento
12.
HNO ; 71(2): 83-91, 2023 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-36592183

RESUMO

BACKGROUND: Calculation of percentage hearing loss (pHV) from the pure-tune audiogram according to Röser in 1973 or from the speech audiogram according to Boenninghaus and Röser in 1973 is a method still applied for quantitative assessment of hearing. However, this is not common for the evaluation of postoperative results of implantable hearing systems. During the regular work-up after cochlear implantation (CI) in Germany, all necessary parameters are available for calculation of pHV either from categorical loudness scaling (pHVKLS) or speech-recognition threshold (pHVFB). OBJECTIVE: The parameters pHVKLS and pHVFB are introduced and calculated from data available from clinical routine. Their potential applicability for assessment of the result of CI is evaluated. MATERIALS AND METHODS: This study comprises retrospective chart review of audiological parameters from 66 CI procedures in one tertiary referral center. pHVKLS was calculated from the equal loudness curve 5 CU, pHVFB from the Freiburg speech test in free field. RESULTS: While pHVKLS shows small variation, the variation in pHVFB is initially larger but decreases over time. Furthermore, starting from initial fitting, the mean pHV shows convergence over time. The difference between pHVFB and pHVKLS is positive and statistically significant. CONCLUSION: It is possible to calculate pHVKLS and pHVFB from routine data. A correlation of the difference between pHVFB and pHVKLS with successful CI performance seems plausible.


Assuntos
Implante Coclear , Implantes Cocleares , Surdez , Perda Auditiva , Percepção da Fala , Humanos , Implante Coclear/métodos , Estudos Retrospectivos , Perda Auditiva/diagnóstico , Perda Auditiva/cirurgia , Surdez/reabilitação , Audiometria de Tons Puros/métodos
13.
Audiol Neurootol ; 27(6): 469-477, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36007501

RESUMO

INTRODUCTION: The common mechanism of tinnitus, hyperacusis, and loudness perception is hypothesized to be related to central gain. Although central gain increases with attempts to compensate hearing loss, reduced input can also be observed in those with clinically normal hearing. This study aimed to evaluate the loudness growth function of tinnitus patients with and without hyperacusis using behavioural and electrophysiological methods. METHODS: The study consists of three groups with a total of 60 clinically normal hearing subjects, including the control group (10 men and 10 women; mean age 39.8, SD 11.8 years), tinnitus group (10 men and 10 women; mean age 40.9, SD 12.2 years), and hyperacusis group (also have tinnitus) (7 men and 13 women; mean age 38.7, SD 14.6 years). Loudness discomfort levels (LDLs), categorical loudness scaling (CLS), and cortical auditory evoked potentials were used for the evaluation of loudness growth. N1-P2 component amplitudes and latencies were measured. RESULTS: LDL results of 500, 1,000, 2,000, 4,000, and 8,000 Hz showed a significant difference between the hyperacusis group and the other two groups (p < 0.001). In the loudness scale test performed with 500 Hz and 2,000 Hz narrow-band noise (NBN) stimulus, a significant difference was observed between the hyperacusis group and the other two groups in the "medium," "loud," and "very loud" categories (p < 0.001). In the cortical examination performed with 500 Hz and 2,000 Hz NBN stimulus at 40, 60, and 80 dB nHL intensities, no significant difference was observed between the groups in the N1, P2 latency, and N1-P2 peak-to-peak amplitude. CONCLUSION: Although the hyperacusis group is significantly different between groups in behavioural tests, the same cannot be said for electrophysiological tests. In our attempt to differentiate tinnitus and hyperacusis with electrophysiological tests over the loudness growth function, N1 and P2 responses were not seen as suitable methods. However, it appears to be beneficial to use CLS in addition to LDLs in behavioural tests.


Assuntos
Hiperacusia , Zumbido , Masculino , Humanos , Feminino , Adulto , Audição , Percepção Sonora/fisiologia , Testes Auditivos
14.
Int J Audiol ; 61(1): 59-65, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33587680

RESUMO

OBJECTIVES: To compare the loudness functions (loudness ratings as a function of sound level) obtained from patients diagnosed as having functional hearing loss (FHL) with those for patients with sensorineural hearing loss (SNHL) and healthy volunteers. DESIGN: Loudness functions for a 1000 Hz tone for patients with FHL and SNHL were assessed based on the categorical loudness scaling method. The data were compared with control data obtained in our facilities. STUDY SAMPLE: 18 patients (33 ears) with FHL and 10 patients (19 ears) with SNHL. RESULTS: For patients with SNHL and healthy volunteers, loudness increased progressively with increasing sound level above the audiometric threshold, with no exceptions. However, for about 70% of the patients with FHL, a different type of loudness function was obtained; the thresholds determined from the loudness function, which were defined as the minimum sound levels at which loudness could be judged, were 10 dB or more lower than the audiometric threshold (>10 dB), and/or the loudness ratings were elevated for a sound at the audiometric threshold. CONCLUSIONS: The results support the hypothesis that patients with FHL often make threshold judgments based on a certain loudness.


Assuntos
Perda Auditiva Funcional , Perda Auditiva Neurossensorial , Audiometria , Limiar Auditivo , Perda Auditiva Neurossensorial/diagnóstico , Humanos , Percepção Sonora
15.
Int J Audiol ; : 1-10, 2022 Dec 13.
Artigo em Inglês | MEDLINE | ID: mdl-36512479

RESUMO

Objective: Distorted loudness perception is one of the main complaints of hearing aid users. Measuring loudness perception in the clinic as experienced in everyday listening situations is important for loudness-based hearing aid fitting. Little research has been done comparing loudness perception in the field and in the laboratory.Design: Participants rated the loudness in the field and in the laboratory of 36 driving actions. The field measurements were recorded with a 360° camera and a tetrahedral microphone. The recorded stimuli, which are openly accessible, were presented in three conditions in the laboratory: 360° video recordings with a head-mounted display, video recordings with a desktop monitor and audio-only.Study samples: Thirteen normal-hearing participants and 18 hearing-impaired participants with hearing aids.Results: The driving actions were rated as louder in the laboratory than in the field for the condition with a desktop monitor and for the audio-only condition. The less realistic a laboratory condition was, the more likely it was for a participant to rate a driving action as louder. The field-laboratory loudness differences were bigger for louder sounds.Conclusion: The results of this experiment indicate the importance of increasing realism and immersion when measuring loudness in the clinic.

16.
Int J Audiol ; 61(10): 868-875, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-34550862

RESUMO

OBJECTIVE: Sound therapy (ST) and stress reduction regimens have been successfully used to manage tinnitus. Virtual reality (VR) has been used to manage chronic conditions like intractable pain. The aim of the present study was to investigate whether the use of VR in conjunction with ST revealed additional improvements in tinnitus attributes as compared to ST alone. DESIGN: This study was a randomised controlled trial (RCT) with a cross-over design. All participants received two interventions - ST alone (control) and ST with VR stimuli (experimental). ST consisted of fractal tones while VR stimuli comprised of nature videos presented via VR goggles. A multilevel mixed-effects linear regression model was used to estimate the intervention effect. STUDY SAMPLE: Twenty adults with subjective, continuous, chronic tinnitus participated in the study. RESULTS: After adjusting for period and baseline tinnitus loudness, significant improvements were observed in tinnitus loudness and Tinnitus Functional Index scores. Although not statistically significant, mean minimum masking levels were lower after the experimental intervention. CONCLUSIONS: Study participants benefitted from the use of VR in conjunction with ST in a laboratory setting. Additional effectiveness trials and blinded RCTs will be needed before validating the use of VR for tinnitus management in clinical settings.


Assuntos
Zumbido , Realidade Virtual , Adulto , Doença Crônica , Humanos , Som , Zumbido/terapia
17.
Hum Brain Mapp ; 42(6): 1742-1757, 2021 04 15.
Artigo em Inglês | MEDLINE | ID: mdl-33544429

RESUMO

Psychoacoustic research suggests that judgments of perceived loudness change differ significantly between sounds with continuous increases and decreases of acoustic intensity, often referred to as "up-ramps" and "down-ramps." The magnitude and direction of this difference, in turn, appears to depend on focused attention and the specific task performed by the listeners. This has led to the suspicion that cognitive processes play an important role in the development of the observed context effects. The present study addressed this issue by exploring neural correlates of context-dependent loudness judgments. Normal hearing listeners continuously judged the loudness of complex-tone sequences which slowly changed in level over time while auditory fMRI was performed. Regression models that included information either about presented sound levels or about individual loudness judgments were used to predict activation throughout the brain. Our psychoacoustical data confirmed robust effects of the direction of intensity change on loudness judgments. Specifically, stimuli were judged softer when following a down-ramp, and louder in the context of an up-ramp. Levels and loudness estimates significantly predicted activation in several brain areas, including auditory cortex. However, only activation in nonauditory regions was more accurately predicted by context-dependent loudness estimates as compared with sound levels, particularly in the orbitofrontal cortex and medial temporal areas. These findings support the idea that cognitive aspects contribute to the generation of context effects with respect to continuous loudness judgments.


Assuntos
Percepção Sonora/fisiologia , Córtex Pré-Frontal/fisiologia , Psicoacústica , Lobo Temporal/fisiologia , Adolescente , Adulto , Córtex Auditivo/diagnóstico por imagem , Córtex Auditivo/fisiologia , Mapeamento Encefálico , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Córtex Pré-Frontal/diagnóstico por imagem , Lobo Temporal/diagnóstico por imagem , Adulto Jovem
18.
Dev Sci ; 24(1): e12982, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32358988

RESUMO

Accurate perception and production of emotional states is important for successful social interactions across the lifespan. Previous research has shown that when identifying emotion in faces, preschool children are more likely to confuse emotions that share valence, but differ in arousal (e.g. sadness and anger) than emotions that share arousal, but differ on valence (e.g. anger and joy). Here, we examined the influence of valence and arousal on children's production of emotion in music. Three-, 5- and 7-year-old children recruited from the greater Hamilton area (N = 74) 'performed' music to produce emotions using a self-pacing paradigm, in which participants controlled the onset and offset of each chord in a musical sequence by repeatedly pressing and lifting the same key on a MIDI piano. Key press velocity controlled the loudness of each chord. Results showed that (a) differentiation of emotions by 5-year-old children was mainly driven by arousal of the target emotion, with differentiation based on both valence and arousal at 7 years and (b) tempo and loudness were used to differentiate emotions earlier in development than articulation. The results indicate that the developmental trajectory of emotion understanding in music may differ from the developmental trajectory in other domains.


Assuntos
Música , Ira , Nível de Alerta , Criança , Pré-Escolar , Emoções , Humanos
19.
Int J Audiol ; 60(5): 350-358, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-33100070

RESUMO

OBJECTIVE: Current hearing aid prescription rules assume that spectral loudness summation decreases with hearing impairment and that binaural loudness summation is independent of hearing loss and signal bandwidth. Previous studies have shown that these assumptions might be incorrect. Spectral loudness summation was measured and compared for loudness scaling and loudness matching. DESIGN: In this study, the effect of bandwidth on binaural summation was investigated by comparing loudness perception of low-pass filtered, high-pass filtered, and broadband pink noise at 35 Categorical Units for both unilateral and bilateral presentation. STUDY SAMPLE: Sixteen hearing-impaired listeners. RESULTS: The results show that loudness differences between the three signals are different for bilateral presentation than for unilateral presentation. In specific, binaural loudness summation is larger for the low-pass filtered pink noise than for the high-pass filtered pink noise. Finally, individual variability in loudness perception near loudness discomfort level was found to be very large. CONCLUSIONS: Loudness matching is offered as a fast and reliable method to measure individual loudness perception. As discomfort with loud sounds is one of the major problems encountered by hearing aid users, measurement of individual loudness perception could improve hearing aid fitting substantially.


Assuntos
Auxiliares de Audição , Perda Auditiva , Estimulação Acústica , Humanos , Percepção Sonora , Ruído/efeitos adversos
20.
Int J Audiol ; 60(8): 607-613, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-33305628

RESUMO

OBJECTIVE: There is currently no singularly accepted definition of hyperacusis. The aim of this study was to determine a definition and description of hyperacusis by clinician consensus. DESIGN: A three-round Delphi survey involving hearing healthcare professionals built towards clinical consensus on a definition of hyperacusis. Round 1 involved three open-ended questions about hyperacusis. Seventy-nine statements were generated on descriptions, impact, sounds, and potential features of hyperacusis. Agreement on the relevance of each statement to defining or describing hyperacusis was then measured in Rounds 2 and 3. General consensus was defined a priori as ≥70% agreement, or ≥90 for clinical decision making. STUDY SAMPLE: Forty-five hearing healthcare professionals were recruited to take part in this study. Forty-one completed Round 1, 36 completed Round 2, and 33 completed Round 3. RESULTS: Consensus was reached on 42/79 statements. From these a consensus definition includes "A reduced tolerance to sound(s) that are perceived as normal to the majority of the population or were perceived as normal to the person before their onset of hyperacusis". A consensus description of hyperacusis was also determined. CONCLUSIONS: This consensus definition of hyperacusis will help to determine the scope of clinical practice guidelines and influence needed research on hyperacusis.


Assuntos
Pessoal de Saúde , Hiperacusia , Consenso , Técnica Delphi , Humanos , Hiperacusia/diagnóstico , Inquéritos e Questionários
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