Effect of an acrylic resin combined with an antimicrobial polymer on biofilm formation
J. appl. oral sci
; 20(6): 643-648, Nov.-Dec. 2012. ilus, tab
Article
em En
| LILACS
| ID: lil-660635
Biblioteca responsável:
BR1.1
ABSTRACT
OBJECTIVES:
The purpose of this study was to evaluate the antimicrobial activity of an acrylic resin combined with an antimicrobial polymer poly (2-tert-butylaminoethyl) methacrylate (PTBAEMA) to inhibit Staphylococcus aureus, Streptococcus mutans and Candida albicans biofilm formation. MATERIAL ANDMETHODS:
Discs of a heat-polymerized acrylic resin were produced and divided according to PTBAEMA concentration 0 (control), 10 and 25%. The specimens were inoculated (10(7) CFU/mL) and incubated at 37ºC for 48 h. After incubation, the wells were washed and each specimen was sonicated for 20 min. Replicate aliquots of resultant suspensions were plated at dilutions at 37ºC for 48 h. The number of colony-forming units (CFU) was counted and expressed as log (CFU+1)/mL and analyzed statistically with α=.05.RESULTS:
The results showed that 25% PTBAEMA completely inhibited S. aureus and S. mutans biofilm formation. A significant reduction of log (CFU+1)/mL in count of S. aureus (control 7.9±0.8A; 10% 3.8±3.3B) and S. mutans (control 7.5±0.7A; 10% 5.1±2.7B) was observed for the group containing 10% PTBAEMA (Mann-Whitney, p<0.05). For C. albicans, differences were not significant among the groups (control 6.6±0.2A; 10% 6.6±0.4A; 25% 6.4±0.1A), (Kruskal-Wallis, p>0.05, P=0.079).CONCLUSIONS:
Acrylic resin combined with 10 and 25% of PTBAEMA showed significant antimicrobial activity against S. aureus and S. mutans biofilm, but it was inactive against the C. albicans biofilm.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Staphylococcus aureus
/
Streptococcus mutans
/
Resinas Acrílicas
/
Candida albicans
/
Biofilmes
/
Metacrilatos
Idioma:
En
Revista:
J. appl. oral sci
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2012
Tipo de documento:
Article
/
Project document
País de afiliação:
Brasil