[Neoadjuvant chemotherapy of patients with breast carcinoma]. / Neoadjuvante Chemotherapie bei Patientinnen mit Mammakarzinom.

ABSTRACT

Adjuvant therapy has shown to be of significant benefit in patients with breast cancer. Among the possibilities to further improve the results, preoperative chemotherapy is a promising tool. So far, we have treated 178 patients and found that downstaging permits breast conservation in 60% of patients who would otherwise undergo mastectomy. The significance of this method for further improvement of survival has to await results of ongoing trials.