Analgesic activity of acylated 2-benzoxazolinone derivatives.
Farmaco
; 54(1-2): 112-5, 1999.
Article
em En
| MEDLINE
| ID: mdl-10321037
ABSTRACT
Ten new benzoxazolinone derivatives having a disubstituted benzoyl group at the six position of the ring were synthesized by reacting 2-benzoxazolinone with aromatic carboxylic acids in the presence of polyphosphoric acid. The structure of the compounds were elucidated by IR, 1H NMR, MS and elemental analysis. Analgesic activity was evaluated by a modified Koster test. Seven compounds showed analgesic activities higher than that of acetylsalicylic acid.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Benzoxazóis
/
Analgésicos não Narcóticos
Limite:
Animals
Idioma:
En
Revista:
Farmaco
Assunto da revista:
FARMACOLOGIA
/
QUIMICA
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Turquia