Indinavir crystallization and urolithiasis.
Int Urol Nephrol
; 31(1): 23-9, 1999.
Article
em En
| MEDLINE
| ID: mdl-10408298
ABSTRACT
The crystallization of indinavir in synthetic urine at different pH values and indinavir concentrations was kinetically studied. It was found that precipitation time notably decreases at urinary pH values above 6.0. The effects of some products as potential crystallization inhibitors were studied. Some natural saponins such as escin and glycyrrhizic acid provoked a notable increase in the precipitation time of indinavir, this pointing out their possible use to prevent renal tubular solid deposition.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Inibidores da Protease de HIV
/
Indinavir
Limite:
Humans
Idioma:
En
Revista:
Int Urol Nephrol
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Espanha