Nitric oxide metabolites in CSF of patients with MS are related to clinical disease course.
Neurology
; 53(8): 1880-2, 1999 Nov 10.
Article
em En
| MEDLINE
| ID: mdl-10563648
ABSTRACT
In this study, we have analyzed the stable metabolites of nitric oxide (NO), nitrite and nitrate, in the CSF of patients with MS, lymphocytic meningitis, and in healthy control subjects. Patients with MS with an active disease course exhibited increased CSF nitrite levels compared with patients with stable MS and healthy control subjects, whereas CSF nitrate levels did not differ between these groups. High CSF levels of both metabolites were seen in patients with meningitis. These data indicate that CSF nitrite levels may reflect clinical disease activity in MS.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esclerose Múltipla
/
Nitratos
/
Óxido Nítrico
/
Nitritos
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Neurology
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Suécia