Reaction times are faster in HIV-seropositive patients on antiretroviral therapy: A preliminary report.
J Clin Exp Neuropsychol
; 21(5): 730-5, 1999 Oct.
Article
em En
| MEDLINE
| ID: mdl-10572290
ABSTRACT
We evaluated subclinical mental and motor slowing in 142 HIV-seropositive patients without dementia, using computerized simple and choice reaction time tasks and self-report measures of psychological distress. Patients on antiretroviral therapy at the time of testing (n = 79) had significantly faster choice reaction times (p < 0.05), indicating faster mental processing speed, than untreated patients (n = 63). These faster RTs could not be attributed to differences in age, education, risk factors, degree of immunosuppression, substance abuse history, peripheral neuropathy, or psychological distress. Reaction time tasks should be investigated further as potential outcome measures in clinical trials, particularly for subjects with few or no overt cognitive deficits.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Desempenho Psicomotor
/
Tempo de Reação
/
Infecções por HIV
/
Cognição
/
Fármacos Anti-HIV
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Clin Exp Neuropsychol
Assunto da revista:
NEUROLOGIA
/
PSICOLOGIA
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Estados Unidos