Cloning, expression, and mapping of PDCD9, the human homolog of Gallus gallus pro-apoptotic protein p52.
Cytogenet Cell Genet
; 87(1-2): 85-8, 1999.
Article
em En
| MEDLINE
| ID: mdl-10640817
ABSTRACT
We report the sequence, tissue distribution, and chromosome location of a novel gene, PDCD9 (programmed cell death 9). PDCD9 is the mammalian counterpart of the Gallus gallus pro-apoptotic protein p52. The human cDNA has an open reading frame of 1,314 nucleotides and was predicted to encode a protein of 438 amino acids with a calculated mass of 50 kDa. The protein sequences of chicken, mouse, and human PDCD9 are remarkably conserved. PDCD9 mRNA is expressed ubiquitously in adult tissues, displaying a stronger signal in heart, skeletal muscle, kidney, and liver. PDCD9 was mapped to chromosome 5q11.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Virais
/
Galinhas
/
Proteínas de Ciclo Celular
/
Mapeamento Físico do Cromossomo
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Cytogenet Cell Genet
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Espanha