[Surgical treatment of hypoplastic left heart syndrome: limited success]. / De operatieve behandeling van het hypoplastisch linkerhartsyndroom: beperkt succes.
Ned Tijdschr Geneeskd
; 145(2): 85-90, 2001 Jan 13.
Article
em Nl
| MEDLINE
| ID: mdl-11225263
ABSTRACT
OBJECTIVE:
To inventory the treatment of hypoplastic left heart syndrome (HLHS) in the Netherlands and its results.DESIGN:
Retrospective.METHOD:
Data were collected from all patients (n = 117) diagnosed with HLHS in the Wilhelmina Children's Hospital-University Medical Center Utrecht and the University Hospital Rotterdam-Sophia Children's Hospital and born in the period 1 March 1988-31 May 2000. Type and time of intervention, and mortality were recorded and cumulative survival was analysed by Kaplan-Meier analysis. Cumulative survival was compared between early and late series and between the two hospitals.RESULTS:
The study group comprised 68 boys and 49 girls, all neonates. At the time of the investigation, the mean duration of follow-up was 185 days (range 0-3855). Fifty-eight children had received no treatment; all of these had died. Fifty-nine children were scheduled for the Norwood procedure; six of them died before operation. The 53 patients who underwent the first stage of the Norwood procedure had 1-month, 1-year, 2-year, and 5-year survival chances of 55%, 30%, 27%, and 24% respectively. Survival chances between the two time periods and the two hospitals showed no significant differences.CONCLUSION:
The Norwood procedure was performed in almost half of the children with HLHS. It is only moderately successful; however, it seems the only realistic choice in the management.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Coração Esquerdo Hipoplásico
/
Procedimentos Cirúrgicos Cardíacos
Tipo de estudo:
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Newborn
País/Região como assunto:
Europa
Idioma:
Nl
Revista:
Ned Tijdschr Geneeskd
Ano de publicação:
2001
Tipo de documento:
Article