Prompt and durable hematopoietic reconstitution by unrelated cord blood transplantation in a child with Fanconi anemia.
Bone Marrow Transplant
; 27(7): 767-9, 2001 Apr.
Article
em En
| MEDLINE
| ID: mdl-11360120
ABSTRACT
We describe here the case of an 8-year-old girl with Fanconi anemia (FA) whose hematopoiesis was successfully restored by unrelated umbilical cord blood (UCB) transplantation. The patient became resistant to androgen therapy, and developed intracranial hemorrhage and dyserythropoiesis. Her hematopoietic recovery after the transplantation was excellent and a complete chimerism has been durably maintained. UCB should be considered as a stem cell source for transplantation when a patient with FA does not have an HLA-identical unaffected sibling donor.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante de Células-Tronco Hematopoéticas
/
Anemia de Fanconi
/
Hematopoese
Tipo de estudo:
Etiology_studies
Limite:
Child, preschool
/
Female
/
Humans
Idioma:
En
Revista:
Bone Marrow Transplant
Assunto da revista:
TRANSPLANTE
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Japão