Spontaneous hemomediastinum complicating steroid-induced mediastinal lipomatosis.
Chest
; 120(1): 311-3, 2001 Jul.
Article
em En
| MEDLINE
| ID: mdl-11451858
ABSTRACT
Spontaneous hemomediastinum is a rare event, occurring in association with bleeding disorders, intratumoral bleeding, or following an abrupt increase in intrathoracic pressure. We report the case of a patient with systemic lupus erythematosus, nephrotic syndrome, and renal failure, in whom mediastinal lipomatosis (ML) developed following increased corticosteroid therapy. Anticoagulant therapy likely precipitated a massive spontaneous hemomediastinum secondary to diffuse hemorrhage of mediastinal fat, which required emergency decompressive surgery. Steroid-induced ML is common and usually well tolerated, but clinicians should be aware of its potential risk of bleeding when associated with anticoagulant therapy. This case further emphasizes the bleeding complications of treatment with low-molecular-weight heparin in patients with renal failure.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prednisona
/
Heparina de Baixo Peso Molecular
/
Glucocorticoides
/
Hemorragia
/
Lipomatose
/
Doenças do Mediastino
/
Anticoagulantes
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Chest
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
França