[Small ovarian cysts in postmenopause: assessment of their malignant potential with vaginal ultrasonography and tumor marker Ca125 titration]. / Piccole cisti ovariche in postmenopausa: valutazione del loro potenziale maligno mediante l'uso di ultrasonografia vaginale e titolazione del marcatore tumorale Ca125.
Minerva Ginecol
; 53(1 Suppl 1): 120-4, 2001 Feb.
Article
em It
| MEDLINE
| ID: mdl-11526706
ABSTRACT
BACKGROUND:
The aim of this study was to determine the risk of malignancy in cystic ovarian tumors < 10 cm in diameter in asymptomatic postmenopausal women.METHODS:
All cystic ovarian tumors, detected by abdominal and transvaginal sonography screening, in asymptomatic postmenopausal women were evaluated with respect to size and morphology. Follow-up data were available both on patients undergoing surgery and on those who elected to be followed without operative intervention. Titration of the tumoral marker Ca125 was carried out, too.RESULTS:
Unilocular cystic tumors were detected in 32 of 352 postmenopausal patients (9%), of 45-65 years of age arrived at the "Centre for diagnosis and therapy of menopausal diseases" of the III Divisione di Ginecologia e Ostetricia della Seconda Università degli Studi di Napoli from the 1st January to the 31st December 1999. All tumors were < 10 cm in diameter and 98% were < 5 cm in diameter; just one tumor was hardly > 5 cm in diameter (5.8), 14 of these cystic ovarian tumors (49%) resolved spontaneously within 60 days while 18 (51%) persisted. Seven patients with persistent cystic ovarian tumors underwent operative tumor removal. Five of these patients had serous cystadenoma and 2 other women had cystoadenofibroma. Not even one case of ovarian carcinoma was found in this group. The remaining 11 patients with unilocular cystic ovarian tumors underwent sonography control every 3 months for one year and no one of these patients developed ovarian carcinoma. In all these patients the dosage of the tumoral marker Ca125 remained under the suspicious threshold of malignant ovaric tumor (Ca125 = 35 U/ml).CONCLUSIONS:
Unilocular cystic ovarian tumors < 5 cm in diameter in asymptomatic postmenopausal women were associated with minimal risk for ovarian cancer. In contrast, complex ovarian cysts wall abnormalities or solid areas are associated with a significant risk for malignancy. These date are important in determining therapeutic optimal strategies in these patients.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cistos Ovarianos
/
Lesões Pré-Cancerosas
/
Pós-Menopausa
/
Antígeno Ca-125
Tipo de estudo:
Diagnostic_studies
Limite:
Aged
/
Female
/
Humans
/
Middle aged
Idioma:
It
Revista:
Minerva Ginecol
Ano de publicação:
2001
Tipo de documento:
Article