DNA structure in sheared and unsheared chromatin.
Science
; 192(4241): 796-8, 1976 May 21.
Article
em En
| MEDLINE
| ID: mdl-1265482
ABSTRACT
Shearing chromatin, by either sonication or vortex homogenization, introduces significant structural artifacts. These may be detected by the anomalously large increase in the number of ethidium bromide binding sites and the large alteration of the circular dichroism spectra of chromatin. Structural alterations are also suggested by the disappearance of differential light scattering after shearing.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA
/
Cromatina
/
Conformação de Ácido Nucleico
Idioma:
En
Revista:
Science
Ano de publicação:
1976
Tipo de documento:
Article