Neurokinin A-like immunoreactivity in articular afferents of the cat.
Brain Res
; 586(2): 332-5, 1992 Jul 24.
Article
em En
| MEDLINE
| ID: mdl-1381653
ABSTRACT
Dorsal root ganglion cells with axons innervating the cat's knee joint via the medial articular nerve were retrogradely labelled with Fast blue. Neurokinin A-like immunoreactivity was found in 4.5 +/- 1.1% (mean +/- S.D. of 5 nerves and 695 cells) of the articular afferents. Colchicine treatment of the ganglia increased the percentage of immunopositive cells to 8.5 +/- 0.7% (mean +/- S.D. of 6 nerves and 554 cells) after 3-22 h. The diameter distribution of the immunopositive somata ranged from 20 to 50 microns with a maximum at 26-30 microns. Comparing the proportions of neurokinin A-immunopositive cells with those of substance P, it can be calculated on the basis of mRNA encoding that neurokinin A is synthetized in about half of the substance P-containing primary articular afferents.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nervos Periféricos
/
Neurocinina A
/
Vias Aferentes
/
Gânglios Espinais
/
Articulações
Limite:
Animals
Idioma:
En
Revista:
Brain Res
Ano de publicação:
1992
Tipo de documento:
Article