Fibrinogen/fibrin in atherogenesis.
Eur J Epidemiol
; 8 Suppl 1: 83-7, 1992 May.
Article
em En
| MEDLINE
| ID: mdl-1387095
ABSTRACT
Fibrin is a major component of many atherosclerotic plaques. Within the intima there is continuous formation of fibrin, and continuous fibrinolysis. In aortic lesions, a lipoprotein bound to fibrin can be released by incubation with plasmin. Most of this lipoprotein is accounted for by Lp(a). The atherogenicity of Lp(a) may be more associated with lipid deposition than with inhibition of fibrinolysis. Fibrin degradation products may be chemotactic to monocyte-macrophages and stimulate smooth muscle cell proliferation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Aorta
/
Doenças da Aorta
/
Arteriosclerose
/
Produtos de Degradação da Fibrina e do Fibrinogênio
/
Fibrinogênio
/
Fibrina
Limite:
Humans
Idioma:
En
Revista:
Eur J Epidemiol
Assunto da revista:
EPIDEMIOLOGIA
Ano de publicação:
1992
Tipo de documento:
Article