Involvement of progenitor cells in vascular repair.
Trends Cardiovasc Med
; 13(8): 322-6, 2003 Nov.
Article
em En
| MEDLINE
| ID: mdl-14596947
ABSTRACT
Whereas the genesis of an arterial lesion is thought to be the result of migration and proliferation of vascular cells, recent insights into the biology of progenitor cells now question this concept. Specifically, endothelial and smooth muscle cells appear to be derived from multiple sources such as circulating stem and progenitor cells, as well as tissue-resident progenitor cell populations. These cells may engraft at sites of vascular injury and play an integral role in vascular repair. In this review, experimental data from in vitro studies, animal models, and scattered human observations are reviewed in the context of emerging hypotheses regarding the response to vascular injury.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células-Tronco
/
Doenças Vasculares
/
Músculo Liso Vascular
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Cardiovasc Med
Assunto da revista:
ANGIOLOGIA
/
CARDIOLOGIA
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Canadá