Sentinel lymphonodectomy in nonmelanoma skin malignancies.
Br J Dermatol
; 149(4): 763-9, 2003 Oct.
Article
em En
| MEDLINE
| ID: mdl-14616367
ABSTRACT
BACKGROUND:
Whereas the value of sentinel lymphonodectomy (SLNE) in malignant melanoma is established, experience with SLNE in nonmelanoma skin cancers is limited.OBJECTIVES:
The feasibility of SLNE in nonmelanoma skin tumours is evaluated.METHODS:
Thirty-seven patients with high-risk nonmelanoma skin tumours underwent SLNE 11 squamous cell carcinomas (SCCs), seven Merkel cell carcinomas (MCCs), five cutaneous lymphomas, eight adnexal carcinomas and six other skin cancers, all clinical stage N0.RESULTS:
In nine patients (four MCCs, two SCCs, three lymphomas) the sentinel lymph nodes (SLNs) showed histological evidence of microinvolvement. In five of these nine patients, radical lymph node dissection (RLND) was performed, revealing further micrometastases in three patients (two SCCs, one MCC). No patient with negative SLN showed tumour dissemination during the follow-up over a mean of 2.5 years (range 2 months to 4.5 years, median 2.4 years).CONCLUSIONS:
Our data provide evidence that SLNE is a minimally invasive and highly sensitive staging tool in selected patients with high-risk nonmelanoma skin cancers.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Biópsia de Linfonodo Sentinela
Tipo de estudo:
Evaluation_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
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Child
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Br J Dermatol
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Alemanha