Up-date on solitary plasmacytoma and its main differences with multiple myeloma.
Exp Oncol
; 27(1): 7-12, 2005 Mar.
Article
em En
| MEDLINE
| ID: mdl-15812350
ABSTRACT
Solitary plasmacytoma is plasma cell neoplasm. It is a localized bone disease and for this reason it is different from multiple myeloma (systemic plasma cell neoplasm). Sometimes, solitary plasmacytoma precedes a following multiple myeloma. Clinical findings of solitary plasmacytoma are related to the univocal localization on damaged bone, while laboratory findings could be similar to multiple myeloma (i.e. M component, kidney dysfunction, blood calcium alterations, increased beta-2-microglobulin). However, during a solitary plasmacytoma, laboratory findings could not be present contemporaneously such clinical complications (i.e. kidney failure, immunological disorders with a trend toward infectious disease and/or autoimmunity, neurological disorders, haematological disorders, amyloidosis, POEMS syndrome). These raise the reason because solitary plasmacytoma has better prognosis compared to multiple myeloma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmocitoma
/
Neoplasias Ósseas
/
Mieloma Múltiplo
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Aged
/
Animals
/
Humans
/
Middle aged
Idioma:
En
Revista:
Exp Oncol
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Itália