Pineal region giant cell astrocytoma associated with tuberous sclerosis: case report.
J Neurosurg
; 102(3 Suppl): 322-5, 2005 Apr.
Article
em En
| MEDLINE
| ID: mdl-15881760
ABSTRACT
Tuberous sclerosis complex is a genetic disorder characterized by the development of hamartomas in multiple organs including the brain, skin, eye, kidney, and heart. Neurological features include seizures and mental retardation. Cortical tubers and subependymal nodules are the characteristic intracranial lesions of tuberous sclerosis. Subependymal giant cell astrocytomas, typically located adjacent to the foramen of Monro, can enlarge and cause symptomatic ventricular obstruction. The authors describe the case of a 3-year-old boy with a history of tuberous sclerosis and retinal lesions who presented with an enlarging enhancing pineal region mass. Via an infratentorial supracerebellar approach, the mass was removed using both the operative microscope and a rigid neuroendoscope. Pathological examination showed a giant cell astrocytoma. To the authors' knowledge, this is the first reported case of tuberous sclerosis associated with a giant cell astrocytoma of the pineal region. Diagnostic considerations are discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pinealoma
/
Astrocitoma
/
Esclerose Tuberosa
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Child, preschool
/
Humans
/
Male
Idioma:
En
Revista:
J Neurosurg
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Estados Unidos