Neurologic syndrome in 25 workers from an aluminum smelting plant.
Arch Intern Med
; 152(7): 1443-8, 1992 Jul.
Article
em En
| MEDLINE
| ID: mdl-1627023
ABSTRACT
BACKGROUND:
This article expands on an earlier series of three patients with a neurologic syndrome, who had all worked in an aluminum smelting plant.METHODS:
Twenty-five symptomatic workers from the same plant were referred for a standardized evaluation, including completion of a health questionnaire, neurologic examination, and neuropsychologic evaluation. An exposure index was calculated for each worker based on level and duration of exposure in the potroom, where exposures were the greatest. This index was correlated with symptoms, signs, and neuropsychologic test scores.RESULTS:
Twenty-two (88%) of the patients reported frequent loss of balance, and 21 (84%) reported memory loss. Neurologic examination revealed signs of incoordination in 21 (84%) of the patients. Neuropsychologic test results showed preservation in certain spheres of functioning, such as verbal IQ, with substantial impairment in others, particularly memory functioning. On memory tests, 70% to 75% showed mild or greater impairment. The majority (17 of 19 tested, or 89%) showed depression on the Minnesota Multiphasic Personality Inventory. The exposure index was significantly correlated with signs and symptoms of incoordination.CONCLUSIONS:
This study and others in humans and animals support the existence of a syndrome characterized by incoordination, poor memory, impairment in abstract reasoning, and depression. Aluminum exposure in the potroom seems the most likely cause.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Alumínio
/
Metalurgia
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Doenças do Sistema Nervoso
/
Doenças Profissionais
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Arch Intern Med
Ano de publicação:
1992
Tipo de documento:
Article