Soft tissue sacrococcygeal chordoma with intracytoplasmic filamentous inclusions.
Pathol Res Pract
; 201(10): 699-704, 2005.
Article
em En
| MEDLINE
| ID: mdl-16325512
ABSTRACT
Extraskeletal chordoma arising within soft tissue is a rare occurrence. We report a case of chordoma that is unusual both for its location within the subcutaneous soft tissue of the sacrococcygeal region without involvement of adjacent bones and for the presence of eosinophilic roundish inclusion bodies within the cytoplasm of tumor cells. These bodies revealed immunoreactivity for cytokeratin and a fibrillar, partly whorled structure on the electron microscopic examination, consistent with an intermediate filament-based composition. To our knowledge, this is the first report of chordoma featuring this cellular change although we do not know the significance of these bodies.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias de Tecidos Moles
/
Cordoma
/
Corpos de Inclusão
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Pathol Res Pract
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Itália