Multiple space-occupying lesions of the spleen in a case of Gaucher's disease.
Intern Med
; 31(4): 557-60, 1992 Apr.
Article
em En
| MEDLINE
| ID: mdl-1633369
ABSTRACT
A 50-year-old female patient was admitted because of an enormously enlarged spleen and thrombocytopenia. Ultrasonography and magnetic resonance imaging revealed multiple space-occupying lesions in the spleen. She was diagnosed as having Gaucher's disease based on the low level of beta-glucosidase activity in leukocytes and Gaucher's cells present in bone marrow aspirate. Severe hypersplenism necessitated splenectomy. Pathological studies of the excised spleen, including ultrastructural examinations, demonstrated that multiple space-occupying lesions in the spleen were composed of typical Gaucher cells.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Baço
/
Doença de Gaucher
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Intern Med
Assunto da revista:
MEDICINA INTERNA
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Japão