Cyclic voltammetric study of alpha-methyldopa at carbon paste electrode.
Pak J Pharm Sci
; 18(1): 6-17, 2005 Jan.
Article
em En
| MEDLINE
| ID: mdl-16431377
ABSTRACT
The cyclic voltammetric behaviour of alpha-methyldopa at a silicon oil carbon paste electrode has been reported. This allowed the development of a quantitative method to determine alpha-methyldopa in LiCl, KCl, NaCl, HCl, H2SO4 and CH3COOH as supporting electrolytes. For qualitative characteristics, alpha-methyldopa showed an ECC mechanism in terms of electron transfer reaction (placing it in DPI zone) at carbon paste electrode. The values of transfer coefficients alpha and beta were determined. The larger DeltaEp values were obtained due to the use of unmodified carbon paste electrode (CPE) has decreased the rate of electron transfer at the surface of the test electrode. The first order rate constant values (ko) were within 0.10-7.78 +/- 0.1x10(-3) s(-1). Adsorption of analyte was also determined at CPE using repeated scan method.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carbono
/
Eletroquímica
/
Metildopa
/
Anti-Hipertensivos
Tipo de estudo:
Qualitative_research
Idioma:
En
Revista:
Pak J Pharm Sci
Assunto da revista:
FARMACIA
/
FARMACOLOGIA
/
QUIMICA
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Paquistão