Limited regression of central giant cell granuloma by interferon alpha after failed calcitonin therapy: a report of 2 cases.
Int J Oral Maxillofac Surg
; 35(9): 865-9, 2006 Sep.
Article
em En
| MEDLINE
| ID: mdl-16584870
ABSTRACT
Central giant cell granuloma (CGCG) is a benign lesion of the jaws with a sometimes locally aggressive behaviour. The most common therapy is surgical curettage which has a high recurrence rate, especially in lesions with aggressive signs and symptoms (i.e. pain, paresthesia, root-resorption and rapid growth). Alternative therapies such as interferon alpha (INFalpha) or calcitonin are described in the literature. In this study 2 patients with an aggressive CGCG are presented who were treated with INF mono-therapy. INF mono-therapy was capable of terminating the rapid growth of the lesion in both patients and induced a partial reduction. Total resolution, however, was not obtained and alternative treatment is still necessary.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Granuloma de Células Gigantes
/
Doenças Mandibulares
/
Doenças Maxilares
/
Interferon-alfa
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Int J Oral Maxillofac Surg
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Holanda