A (9;11)(q34;q13) translocation in a hibernoma.
Cancer Genet Cytogenet
; 170(2): 163-6, 2006 Oct 15.
Article
em En
| MEDLINE
| ID: mdl-17011989
ABSTRACT
The diagnosis of hibernoma has historically been made by histopathologic examination and finding of characteristic brown fat cells with granular multivacuolated cytoplasm. The diagnosis of hibernoma may be complicated, however, because seemingly diagnostic cells could be mistakenly identified as lipoblasts, leading to the erroneous diagnosis of well-differentiated liposarcoma. Cytogenetic alterations in lipomatous tumors are well established and could be used for diagnostic purposes. Previous cytogenetic abnormalities reported in hibernomas have included alteration of 11q13 region. Here, we present a case of a hibernoma with a novel cytogenetic alteration involving a reciprocal translocation between 9q and 11q that was useful in establishing the final diagnosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Coxa da Perna
/
Translocação Genética
/
Cromossomos Humanos Par 9
/
Cromossomos Humanos Par 11
/
Lipoma
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Cancer Genet Cytogenet
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Estados Unidos