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An epidemiologic study of smoking and primary infertility in women.
Laurent, S L; Thompson, S J; Addy, C; Garrison, C Z; Moore, E E.
Afiliação
  • Laurent SL; Department of Obstetrics and Gynecology, Carolinas Medical Center, Charlotte, North Carolina 28232-2861.
Fertil Steril ; 57(3): 565-72, 1992 Mar.
Article em En | MEDLINE | ID: mdl-1740199
ABSTRACT

OBJECTIVE:

To determine the relationship between cigarette smoking and primary female infertility.

DESIGN:

Retrospective, case-control study.

SETTING:

Population-based and randomly selected from eight geographic areas in the United States.

PARTICIPANTS:

Women, 20 to 54 years of age, who were randomly selected to serve as the control group of the Cancer and Steroid Hormone Study were used for this study. Within this group, there were 483 women who were classified as having experienced primary infertility and 2,231 women eligible to serve as controls. Primary infertility, defined as 24 consecutive months of unprotected intercourse without conception, was documented from a calendar of each women's reproductive and contraceptive history.

RESULTS:

Smoking one pack of cigarettes per day (odds ratio = 1.36) and starting to smoke before 18 years of age (odds ratio = 1.30) were significantly associated with increased risk of infertility. Life table and proportional hazards analysis indicated that smoking did not significantly increase the time required to conceive among infertile women.

CONCLUSIONS:

Number of cigarettes smoked and age when the women began smoking contributed to infertility in this study. It is reasonable, therefore, to recommend that women stop smoking when they are attempting to become pregnant.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fumar / Infertilidade Feminina Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Fertil Steril Ano de publicação: 1992 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fumar / Infertilidade Feminina Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Fertil Steril Ano de publicação: 1992 Tipo de documento: Article