[The risk of affective disorders among patients with adrenocortical insufficiency: secondary publication]. / Risiko for udvikling af affektive lidelser hos patienter med binyrebarkinsufficiens--sekundaerpublikation.

ABSTRACT

The aim was to investigate the risk of affective disorders among patients with adrenocortical insufficiency. Two cohorts were identified with admission data recorded in Danish hospital registers from 1977 to 1999 one comprising all patients who were first-time hospitalised with adrenocortical insufficiency, the other a control cohort of patients with osteoarthritis. The patients with adrenocortical insufficiency had a 2.68 (95% CI 1.62-4.42) greater rate of depression or mania than the control patients. Thus, adrenocortical insufficiency seems to be linked to an increased risk of affective disorders.