Physiology and pathology of collagen receptors.
Acta Physiol (Oxf)
; 190(3): 179-87, 2007 Jul.
Article
em En
| MEDLINE
| ID: mdl-17581134
ABSTRACT
Just before the transition from pre-genomic to the post-genomic era, the two latest members of the mammalian integrin family were identified. These integrins, which were named alpha10beta1 and alpha11beta1, are both collagen receptors and are related. Rather than being twins, they can be regarded as close cousins. They both belong to the subfamily of integrins that contain an I-domain in the alpha subunit. This domain is also the part that endows these integrins with the capacity to bind the GFOGER sequence in collagens. In the current review, we summarize and update the current knowledge about the in vitro and in vivo functions of these integrins.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Integrinas
/
Receptores de Colágeno
Limite:
Animals
Idioma:
En
Revista:
Acta Physiol (Oxf)
Assunto da revista:
FISIOLOGIA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Noruega