Frontal brain asymmetry and immune function.
Behav Neurosci
; 105(6): 860-9, 1991 Dec.
Article
em En
| MEDLINE
| ID: mdl-1777105
ABSTRACT
The relation between brain activity and the immune system was evaluated by assessing immune responses in 20 healthy women who manifested extreme differences in the asymmetry of frontal cortex activation. One group showed extreme and stable left frontal activation; the other group showed extreme and stable right frontal activation. As predicted, women with extreme right frontal activation had significantly lower levels of natural killer cell activity (at effectortarget cell ratios of 331 and 111) than did left frontally activated individuals. This difference did not extend to two other immune measures, lymphocyte proliferation and T-cell subsets. However, higher immunoglobulin levels of the M class were observed in the right frontal group. In this study, the immune patterns could not be accounted for by plasma cortisol levels, anxiety- and depression-related symptomatology, or recent health histories. These findings support the hypothesis that there is a specific association between frontal brain asymmetry and certain immune responses.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dominância Cerebral
/
Lobo Frontal
/
Sistema Imunitário
/
Imunocompetência
Tipo de estudo:
Prognostic_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Behav Neurosci
Ano de publicação:
1991
Tipo de documento:
Article