Influences of perinatal dioxin load to visual motion and oddball stimuli examined with an EEG and MEG analysis.
Clin Neurophysiol
; 119(7): 1486-95, 2008 Jul.
Article
em En
| MEDLINE
| ID: mdl-18450506
ABSTRACT
OBJECTIVE:
With MEG and EEG the effect of perinatal dioxin load of 38 healthy 7- to 12-year-old children was studied to assess possible disturbances of visual development.METHODS:
Latencies and amplitudes of the motion (N2 with subcomponents) and oddball responses (N200 and P3b) were analysed after age correction.RESULTS:
With increasing load, latencies increased and the amplitudes of the oddball components tended to be reduced. The latency increase between the high- and low-loaded children was about 13 ms (P<0.004) and the oddball response showed an amplitude decrease of 12% (P=0.009).CONCLUSIONS:
It may be concluded that, during the end-80s/early-90s, exposure to background levels in industrialized regions seems to have resulted in small underdevelopment or damage to visual motion processing and visual cognition.SIGNIFICANCE:
Since dioxin pollution by incinerators still exists in many regions in developing countries and also still, although at a smaller scale, in the industrialized world, perinatal loads of similar magnitude and possibly more as measured in this study may occur and as a consequence might affect the developing brain.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Efeitos Tardios da Exposição Pré-Natal
/
Desempenho Psicomotor
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Percepção Visual
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Magnetoencefalografia
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Deficiências do Desenvolvimento
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Dioxinas
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Eletroencefalografia
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Poluentes Ambientais
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Percepção de Movimento
Limite:
Child
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Female
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Humans
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Male
/
Newborn
/
Pregnancy
País/Região como assunto:
Europa
Idioma:
En
Revista:
Clin Neurophysiol
Assunto da revista:
NEUROLOGIA
/
PSICOFISIOLOGIA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Holanda