The relationship between malignant mesothelioma and an asbestos cement plant environmental risk: a spatial case-control study in the city of Bari (Italy).
Int Arch Occup Environ Health
; 82(4): 489-97, 2009 Mar.
Article
em En
| MEDLINE
| ID: mdl-18810484
ABSTRACT
OBJECTIVES:
To estimate the mesothelioma risk and environmental asbestos exposure (EAE) due to an asbestos-cement plant.METHODS:
A spatial case-control study including 48 malignant mesothelioma (MM) cases occurred in the period 1993-2003 selected from the regional mesothelioma register (RMR) and 273 controls. The disease risk was estimated by means of a logistic-regression model, in which the probability of disease-occurrence is expressed as a function of the classes of distances. A non-parametric method was applied to estimate the full relative risk surface.RESULTS:
Significant MM odds ratio of 5.29 (95 CI 1.18-23.74) was found for people living within a range up to 500 m centered on the plant. The non-parametric estimation of relative risk surface unveiled a marked peak near the plant not paralleled by the spatial distribution of controls.CONCLUSION:
Evidence of an association between mesothelioma risk and EAE is highlighted. The role played by the RMR in increasing the public health local authorities awareness is stressed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Amianto
/
Poluentes Atmosféricos
/
Exposição Ambiental
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Neoplasias Pulmonares
/
Mesotelioma
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Int Arch Occup Environ Health
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Itália