Effect of TNF priming of murine peritoneal macrophages on their activation to a tumoricidal state.
Immunol Lett
; 28(2): 127-33, 1991 May.
Article
em En
| MEDLINE
| ID: mdl-1909301
ABSTRACT
Murine peritoneal macrophages, on treatment with TNF (10 U/ml) for various durations, showed enhanced cyototoxicity against tumor target cells. The macrophage-mediated cytotoxicity was significantly enhanced when TNF-primed macrophages were treated with cisplatin, LPS, FK-565 or interferon-gamma for 24 h, compared to unprimed and treated macrophages. TNF-primed macrophages also showed enhanced expression of interleukin-1 and tumor necrosis factor activities on activation with different biological response modifiers.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fator de Necrose Tumoral alfa
/
Ativação de Macrófagos
Limite:
Animals
Idioma:
En
Revista:
Immunol Lett
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Índia