[Larrea tridentata. Effect on a non-metabolic model of urolithiasis in rats]. / Larrea tridentata en urofitiasls. Efecto en un modelo no metabólico en ratas.
Rev Med Inst Mex Seguro Soc
; 46(5): 519-22, 2008.
Article
em Es
| MEDLINE
| ID: mdl-19241660
ABSTRACT
OBJECTIVE:
To evaluate the effect of L. tridentata infusion on the development of urinary calculi in a non-metabolic model.METHODS:
Male Wistar rats were divided into two groups (n = 10 each). The experimental group received 1 mL of oral L. tridentata infusion three times daily for 95 days. Control group received 1 mL tap water. Five days after initiating treatment, urolithiasis was induced inserting a series of 15 knots of 5-0 chromic catgut into the urinary bladder. Measurements included body weight and water intake, complete blood counts, glucose, BUN, creatinine, bacterial culture, and weight of urinary stones and sands.RESULTS:
No statistically significant differences were found between groups for any variable.CONCLUSIONS:
An infusion of L. tridentata was not effective in the prevention of urolith formation in the suture-induced rat model. It produced no alterations in body weight gain, blood counts, or water intake. Future work is needed to completely rule out any effect of the plant on urolith formation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Preparações de Plantas
/
Larrea
/
Urolitíase
/
Fitoterapia
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
Es
Revista:
Rev Med Inst Mex Seguro Soc
Assunto da revista:
MEDICINA
/
MEDICINA SOCIAL
Ano de publicação:
2008
Tipo de documento:
Article