Comorbidities, therapy, and newly diagnosed conditions for women with early stage breast cancer.
J Cancer Surviv
; 3(2): 89-98, 2009 Jun.
Article
em En
| MEDLINE
| ID: mdl-19437121
ABSTRACT
PURPOSE:
To describe comorbidities in breast cancer patients at diagnosis and examine factors associated with self-reported comorbidities 30 months post-diagnosis.METHODS:
Nine hundred forty one of 1,171 women had a medical record abstract and a follow-up survey in the Health, Eating, Activity and Lifestyle Study.RESULTS:
We compared our breast cancer cohort to a contemporaneous nationally-representative sample of age, race/ethnicity and education matched women without cancer (n = 865). Breast cancer patients did not have substantially more comorbidities than women without breast cancer. Women with a hospital record of congestive heart failure significantly less often received chemotherapy or radiation following breast conserving surgery. In multivariate analysis, women who received chemotherapy alone (OR = 3.2; 95% CI 1.5-6.8), chemotherapy plus radiation (OR = 1.9; 95% CI 1.02-3.7) or radiation plus tamoxifen (OR = 1.9; 95% CI 1.1-3.2) were significantly more likely to report at least one new comorbid condition following breast cancer diagnosis than women who received no chemotherapy, tamoxifen or radiation. Overall, women who received adjuvant therapy were more likely to have new comorbidities.CONCLUSIONS:
Comorbidities were not substantially different in breast cancer patients than the non-cancer matched controls. Future research should focus on efforts to minimize comorbidities related to chemotherapy and other combination therapy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
/
Female
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Humans
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Middle aged
País/Região como assunto:
America do norte
Idioma:
En
Revista:
J Cancer Surviv
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Estados Unidos